人血清白蛋白单克隆抗体

英文名称 Serum albumin (3F4)
中文名称 人血清白蛋白单克隆抗体
别 名 ALB; ALBU_HUMAN; Albumin (32 AA); Albumin (AA 34); Analbuminemia; Bisalbuminemia; Cell growth inhibiting protein 42; DKFZp779N1935; Dysalbuminemic hyperthyroxinemia; Growth inhibiting protein 20; HSA; Hyperthyroxinemia dysalbuminemic; PRO0883; PRO0903; PRO1341; PRO2044; PRO2619; Serum albumin.
人血清白蛋白单克隆抗体
说 明 书 0.1ml 0.2ml 1ml
研究领域 细胞生物 免疫学
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 3F4
交叉反应 Human,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 human Serum albumin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
人血清白蛋白单克隆抗体
产品介绍 background:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Post-translational modifications:
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

DISEASE:
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Similarity:
Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.
人血清白蛋白单克隆抗体
zk-7588R A4GALTα1,4-半乳糖基转移酶1
zk-7642R AGTRAP血管紧张素Ⅱ受体相关蛋白抗体
zk-7669R AX2R膜粘连蛋白2受体抗体
zk-0203R ACEI血管紧张素1转换酶抑制剂抗体
zk-1229R AATF拮抗凋亡转录因子抗体
zk-0094R AACT-Alpha1α-1抗胰糜蛋白酶抗体
zk-0096R alpha 1 Antitrypsinα-1抗胰蛋白酶抗体
zk-1224R ABCB6ATP结合蛋白家族6抗体
zk-1231R ABCG1三磷酸腺苷结合盒亚家族G1抗体
zk-0611R Adiponectin receptor 2脂联素受体2抗体
zk-9741R ANGEL1ANGEL1蛋白抗体
zk-9742R ANGEL2ANGEL2蛋白抗体
zk-9743R ANKLE2ANKLE2蛋白抗体
zk-9744R ANKMY1睾丸特异性锚样蛋白1抗体
zk-9745R ANKRD13B锚蛋白重复结构域蛋白13B抗体
zk-9746R ANKRD20A1锚蛋白重复结构域蛋白20A1抗体
zk-9747R ANKRD20A3锚蛋白重复结构域蛋白20A3抗体
zk-9748R ANKRD22锚蛋白重复结构域蛋白22抗体
zk-9751R ANKRD50锚蛋白重复结构域蛋白50抗体
zk-9753R ATP6V1G2氢离子转运ATP合成酶6G抗体
zk-9755R ANKRD26锚蛋白重复结构域蛋白26抗体
zk-9756R ANKRD26锚蛋白重复结构域蛋白26抗体
zk-0728R ACY3丙型肝炎病毒核结合蛋白-1抗体
zk-9102R ARSK芳香基硫酸酯酶K抗体
zk-2409R Amphiphysin神经元突触前膜蛋白抗体
zk-2415R Ankyrin G锚定蛋白G抗体
zk-0189R Actin肌动蛋白α/α-SMA/α Actin抗体
zk-1208R ADAMTS1整合素样金属蛋白酶与凝血酶1型抗体
zk-0733R ADAMTS7(NT)整合素样金属蛋白酶与凝血酶1型-7抗体 (N端抗体)
zk-0433R ADAMTS7整合素样金属蛋白酶与凝血酶1型-7抗体
zk-1114R beta Adducin内收蛋白抗体
zk-1164R ADFP脂肪组织分化相关蛋白抗体
zk-0610R Adiponectin Receptor 1脂联素受体1抗体
zk-0090R ADM R肾上腺髓质素受体抗体
zk-0471R Adiponectin脂联素抗体