STAT6 monoclonal antibody (M01), clone 6C10

STAT6 monoclonal antibody (M01

), clone 6C10
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  • ¥3500¥2800实时议价
  • Abnova已认证
  • ABN-H00006778-M01
  • 中国台湾
  • 2025年11月12日
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 供应商

      艾美捷

    • 库存

      5

    • 克隆性

      单克隆

    • 标记物

      In 1x PBS, pH 7.4

    • 宿主

      Mouse

    • 适应物种

      Human

    • 亚型

      IgG2b Kappa

    • 保存条件

      Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

    • 规格

      100ug

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant STAT6.MAB,monoclonal Ab,monoclonal antibody

    Immunogen

    STAT6 (NP_003144, 694 a.a. ~ 801 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    PPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQD

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG2b Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (37.51 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

    Entrez GeneID

    6778

    GeneBank Accession#

    BC004973

    Protein Accession#

    NP_003144

    Gene Name

    STAT6

    Gene Alias

    D12S1644, IL-4-STAT, STAT6B, STAT6C

    Gene Description

    signal transducer and activator of transcription 6, interleukin-4 induced

    Omim ID

    601512

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq

    Other Designations

    STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT

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