- 询价
- InvivoCrown
- 英国
- SIM0615-1mg
- 2025年11月10日
- ELISA, FACS, Functional assay, Research in vivo
- Human
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
该BioSIM 抗人 PD-L1/CD274 抗体，生物类似药，科研用途的免疫原请参考该产品的说明书
- 保存条件：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别：
科研级别
- 库存：
999
- 供应商：
亚科因(Abbkine)
- 宿主：
Human
- 应用范围：
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名：
PD-L1/CD274
- 抗体名：
PD-L1/CD274
- 规格：
1mg
BioSIM 抗人 PD-L1/CD274 抗体
产品名称：BioSIM anti-Human PD-L1/CD274 Antibody (BMS-936559/MDX-1105 Biosimilar), Research Grade
货号：SIM0615-1mg
规格：1mg
供应商：InvivoCrown
产品概述
BioSIM 抗人 PD-L1/CD274 抗体是一种高质量的生物类似药，专为科研用途设计。该抗体是针对程序性死亡配体-1(PD-L1，也称为CD274)的高特异性抗体，可作为原研抗体BMS-936559/MDX-1105的科研替代品，广泛应用于肿瘤免疫学领域的研究。
产品特点
- 重组生物类似抗体，具有高度特异性
- 在无动物成分的设施中生产，降低动物源污染风险
- 采用体外无蛋白细胞培养技术，减少批次间差异
- 多步骤纯化工艺，包括Protein A或G色谱层析，确保高纯度
- 来源宿主：人源化
- 反应性：人源PD-L1/CD274
研究领域
该抗体主要应用于以下癌症研究领域：
- 小细胞肺癌
- 肝癌
- 结肠癌
应用类型
BioSIM 抗人 PD-L1/CD274 抗体适用于多种实验方法：
- ELISA：用于定量检测样本中PD-L1蛋白表达水平
- FACS：流式细胞术分析细胞表面PD-L1表达
- Functional assay：功能实验，研究PD-L1/PD-1通路调控机制
- Research in vivo：体内研究，评估肿瘤微环境中PD-L1的功能
技术参数
| 产品类型 | 二抗 |
| 免疫原 | 请参考产品说明书 |
| 储存条件 | -20℃避光保存，避免反复冻融 |
| 稀释建议 | 请根据具体实验优化，推荐起始稀释比例为1:100 |
注意事项
本产品仅限科研使用，不可用于临床诊断或治疗。请在使用前仔细阅读产品说明书，并根据实验需求进行适当优化。实验结果可能因实验条件、样本类型等因素而异。
注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。
BioSIM Anti-Human PD-L1/CD274 Antibody
Product Name: BioSIM anti-Human PD-L1/CD274 Antibody (BMS-936559/MDX-1105 Biosimilar), Research Grade
Product No.: SIM0615-1mg
Specification: 1mg
Supplier: InvivoCrown
Product Overview
The BioSIM anti-Human PD-L1/CD274 antibody is a high-quality biosimilar designed specifically for research purposes. This antibody is a highly specific antibody against programmed death ligand-1 (PD-L1, also known as CD274) and can serve as a research substitute for the original antibody BMS-936559/MDX-1105, widely applied in research in the field of tumor immunology.
Product Features
- Recombinant biosimilar antibody with high specificity
- Produced in an animal-component-free facility, reducing the risk of animal-derived contamination
- Adopts in vitro protein-free cell culture technology to reduce batch-to-batch variations
- Multi-step purification process, including Protein A or G chromatography, ensuring high purity
- Source host: Humanized
- Reactivity: Human PD-L1/CD274
Research Fields
This antibody is mainly applied in the following cancer research fields:
- Small cell lung cancer
- Hepatocellular carcinoma
- Colon cancer
Application Types
The BioSIM anti-Human PD-L1/CD274 antibody is suitable for various experimental methods:
- ELISA: Used for quantitative detection of PD-L1 protein expression levels in samples
- FACS: Flow cytometry analysis of PD-L1 expression on cell surfaces
- Functional assay: Functional experiments to study the regulatory mechanism of the PD-L1/PD-1 pathway
- Research in vivo: In vivo studies to evaluate the function of PD-L1 in the tumor microenvironment
Technical Parameters
| Product Type | Secondary antibody |
| Immunogen | Please refer to the product manual |
| Storage Conditions | Store at -20℃ in the dark, avoid repeated freezing and thawing |
| Dilution Suggestion | Please optimize according to specific experiments. The recommended initial dilution ratio is 1:100 |
Precautions
This product is for research use only and cannot be used for clinical diagnosis or treatment. Please carefully read the product manual before use and make appropriate optimizations according to experimental requirements. Experimental results may vary depending on experimental conditions, sample types, etc.
Note: The above information may change due to product optimization and upgrading. For specific information, please consult Yakeyin Company.
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