BioSIM 抗人 IL1RAP 抗体，生物类似药 5mg

BioSIM 抗人 IL1RAP 抗体，生物类似药，科研用途

产品概述

BioSIM anti-Human IL1RAP Antibody (CAN10 Biosimilar) 是一款高质量的二抗，专为科研用途设计。作为CAN10抗体的生物类似药，该产品在无动物成分的生产环境中通过先进的体外无蛋白细胞培养技术制备，并经过Protein A或G色谱工艺的多步骤纯化，确保高纯度和批次一致性。

产品信息

• 产品名称：BioSIM 抗人 IL1RAP 抗体，生物类似药，科研用途
• 供应商：InvivoCrown
• 产品货号：SIM0564-5mg
• 产品规格：5mg
• 来源宿主：Human
• 反应性：Human

IL1RAP研究背景

白细胞介素-1受体辅助蛋白(IL1RAP)是IL-1信号通路中的关键共受体，在多种炎症性疾病和癌症中扮演重要角色。研究表明，IL1RAP在非小细胞肺癌(NSCLC)、胰腺导管腺癌(PDAC)、骨髓增生异常综合征和急性髓细胞样白血病等多种疾病中表达异常，使其成为相关疾病机制研究和潜在治疗靶点的重要分子标志物。

应用领域

该抗体适用于多种研究应用，包括：

• ELISA：可用于IL1RAP的定量检测和表达分析
• FACS：适用于流式细胞术，可用于细胞表面IL1RAP的表达分析和分选
• Functional assay：可用于IL1RAP介导的信号通路功能研究
• Research in vivo：适用于动物模型研究，评估IL1RAP在疾病进展中的作用

研究领域应用

该抗体特别适用于以下疾病研究：

• 非小细胞肺癌(NSCLC)的发病机制研究
• 胰腺导管腺癌(PDAC)的肿瘤微环境分析
• 骨髓增生异常综合征的病理机制探索
• 急性髓细胞样白血病的靶向治疗研究

产品质量特点

• 在无动物成分设施中生产，减少批次间变异和潜在污染风险
• 采用体外无蛋白细胞培养技术，避免动物源成分干扰实验结果
• 多步骤纯化工艺，包括Protein A或G色谱，确保高纯度和低背景信号
• 专为科研设计，提供可靠且可重复的实验结果

保存建议

为确保产品质量和稳定性，请遵循以下保存条件：

• 避免反复冻融，以保持抗体活性
• 短期保存（1-2周）：4°C
• 中期保存（最长12个月）：-20°C
• 长期保存：-80°C

使用说明

该抗体为科研用途设计，具体使用方法和最佳稀释比例请参考产品说明书。免疫原信息请参考产品说明书。在使用前，建议进行小规模测试以确定最佳实验条件。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human IL1RAP Antibody, Biosimilar, for Research Use

Product Overview

BioSIM anti-Human IL1RAP Antibody (CAN10 Biosimilar) is a high-quality secondary antibody designed for research purposes. As a biosimilar of the CAN10 antibody, this product is prepared using advanced animal component-free in vitro cell culture technology in a production environment free of animal components, and undergoes multi-step purification via Protein A or G chromatography to ensure high purity and batch-to-batch consistency.

Product Information

• Product Name: BioSIM anti-Human IL1RAP Antibody, Biosimilar, for Research Use
• Supplier: InvivoCrown
• Catalog Number: SIM0564-5mg
• Product Size: 5mg
• Host: Human
• Reactivity: Human

IL1RAP Research Background

Interleukin-1 receptor accessory protein (IL1RAP) is a key co-receptor in the IL-1 signaling pathway and plays an important role in various inflammatory diseases and cancers. Studies have shown that IL1RAP is abnormally expressed in multiple diseases such as non-small cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC), myelodysplastic syndromes, and acute myeloid leukemia, making it an important molecular marker for related disease mechanism research and potential therapeutic targets.

Application Areas

This antibody is suitable for various research applications, including:

• ELISA: Can be used for quantitative detection and expression analysis of IL1RAP
• FACS: Suitable for flow cytometry, can be used for expression analysis and sorting of cell surface IL1RAP
• Functional assay: Can be used for functional research of IL1RAP-mediated signaling pathways
• Research in vivo: Suitable for animal model studies to evaluate the role of IL1RAP in disease progression

Research Area Applications

This antibody is particularly suitable for the study of the following diseases:

• Research on the pathogenesis of non-small cell lung cancer (NSCLC)
• Tumor microenvironment analysis of pancreatic ductal adenocarcinoma (PDAC)
• Exploration of pathological mechanisms in myelodysplastic syndromes
• Targeted therapy research for acute myeloid leukemia

Product Quality Features

• Produced in animal component-free facilities to reduce inter-batch variation and potential contamination risks
• Uses animal-free in vitro cell culture technology to avoid interference from animal-derived components in experimental results
• Multi-step purification process, including Protein A or G chromatography, ensuring high purity and low background signal
• Designed specifically for research purposes, providing reliable and reproducible experimental results

Storage Recommendations

To ensure product quality and stability, please follow the following storage conditions:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term storage (1-2 weeks): 4°C
• Medium-term storage (up to 12 months): -20°C
• Long-term storage: -80°C

Instructions for Use

This antibody is designed for research purposes. Please refer to the product manual for specific usage methods and optimal dilution ratios. Please refer to the product manual for immunogen information. Before use, it is recommended to perform a small-scale test to determine optimal experimental conditions.

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yaokeen Company.