- 询价
- InvivoCrown
- 英国
- SIM0540-5mg
- 2025年11月10日
- ELISA, FACS, Functional assay, Research in vivo
- Humanized
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
该BioSIM 抗人 PCSK9 抗体 (昂戈瑞西单抗)，生物类似药，科研用途 [ CAS: 2145096-91-7]的免疫原请参考该产品的说明书
- 保存条件：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别：
科研级别
- 库存：
999
- 供应商：
亚科因(Abbkine)
- 宿主：
Humanized
- 应用范围：
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名：
PCSK9
- 抗体名：
PCSK9
- 规格：
5mg
BioSIM 抗人 PCSK9 抗体 (昂戈瑞西单抗)，生物类似药，科研用途
产品概览
BioSIM anti-Human PCSK9 Antibody (昂戈瑞西单抗) 是一种高品质的生物类似药抗体，专为科研用途设计。该抗体源自人源化表达系统，针对人PCSK9蛋白具有高特异性亲和力，适用于多种免疫学检测和研究应用。
基本信息
- 产品名称：BioSIM anti-Human PCSK9 Antibody (Ongericimab Biosimilar), Research Grade
- 产品类型：二抗
- 供应商：InvivoCrown
- 产品货号：SIM0540-5mg
- 产品规格：5mg
- CAS号：2145096-91-7
- 来源宿主：Humanized
- 反应性：Human
产品特点
- 重组生物类似抗体，具有与原研药物相似的分子结构
- 在无动物成分的设施中生产，确保无动物源污染
- 采用体外无蛋白细胞培养技术，降低批次间差异
- 经过多步骤纯化工艺，包括Protein A/G亲和层析，确保高纯度
- 适用于多种研究平台，包括体外和体内实验
研究领域
该抗体主要应用于原发性高胆固醇血症的研究领域，特别适用于PCSK9信号通路、脂质代谢机制以及相关疾病模型的探索。PCSK9作为胆固醇代谢调节的关键蛋白，已成为心血管疾病研究的重要靶点。
应用类型
- ELISA：适用于PCSK9蛋白的定量检测
- FACS：可用于细胞表面PCSK9表达的流式细胞术分析
- Functional assay：适用于功能研究，评估PCSK9对细胞代谢的影响
- Research in vivo：适用于动物模型研究，探索PCSK9在体内的生物学功能
储存与处理建议
- 收到产品后，请避免反复冻融，以保持抗体活性
- 短期储存（1-2周）：4°C保存
- 中期储存（最长12个月）：-20°C保存
- 长期储存：-80°C保存
- 建议分装保存，避免多次取用导致抗体降解
订购信息
产品货号：SIM0540-5mg | 规格：5mg | 供应商：InvivoCrown
如需了解更多技术细节或订购信息，请参考产品说明书或联系我们的技术支持团队。
注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。
BioSIM anti-Human PCSK9 Antibody (Ongericimab Biosimilar), Research Use
Product Overview
BioSIM anti-Human PCSK9 Antibody (Ongericimab) is a high-quality biosimilar antibody designed specifically for research purposes. This antibody is derived from a humanized expression system and exhibits high specific affinity for human PCSK9 protein, making it suitable for various immunological assays and research applications.
Basic Information
- Product Name: BioSIM anti-Human PCSK9 Antibody (Ongericimab Biosimilar), Research Grade
- Product Type: Secondary Antibody
- Supplier: InvivoCrown
- Catalog Number: SIM0540-5mg
- Product Specification: 5mg
- CAS Number: 2145096-91-7
- Source Host: Humanized
- Reactivity: Human
Product Features
- Recombinant biosimilar antibody with similar molecular structure to the original drug
- Produced in animal-free facilities to ensure no animal-derived contamination
- Uses protein-free cell culture technology in vitro to reduce batch-to-batch variation
- Purified through multi-step process including Protein A/G affinity chromatography to ensure high purity
- Compatible with multiple research platforms including in vitro and in vivo experiments
Research Areas
This antibody is primarily applied in research on primary hypercholesterolemia, particularly suitable for exploring PCSK9 signaling pathways, lipid metabolism mechanisms, and related disease models. As a key protein in cholesterol metabolism regulation, PCSK9 has become an important target in cardiovascular disease research.
Application Types
- ELISA: Suitable for quantitative detection of PCSK9 protein
- FACS: Can be used for flow cytometry analysis of PCSK9 expression on cell surfaces
- Functional assay: Suitable for functional studies to evaluate the effects of PCSK9 on cellular metabolism
- Research in vivo: Suitable for animal model studies to explore the biological functions of PCSK9 in vivo
Storage and Handling Recommendations
- Upon receipt, avoid repeated freeze-thaw cycles to maintain antibody activity
- Short-term storage (1-2 weeks): Store at 4°C
- Medium-term storage (up to 12 months): Store at -20°C
- Long-term storage: Store at -80°C
- It is recommended to store in aliquots to avoid degradation from repeated use
Ordering Information
Catalog Number: SIM0540-5mg | Specification: 5mg | Supplier: InvivoCrown
For more technical details or ordering information, please refer to the product manual or contact our technical support team.
Note: The above information may be subject to changes due to product optimization and upgrades. Please consult Yaokein Company for specific information.
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