BioSIM 抗人 PCSK9 抗体 (雷泮赛珠单抗)，生物

BioSIM 抗人 PCSK9 抗体 (雷泮赛珠单抗)，生物类似药

产品概述

BioSIM 抗人 PCSK9 抗体 (雷泮赛珠单抗) 是一种高质量的生物类似药，专为科研用途设计。该抗体针对人类PCSK9蛋白，货号SIM0538-1mg，规格为1mg，由InvivoCrown公司生产。PCSK9(前蛋白转化酶枯草杆菌蛋白酶/kexin type 9)是胆固醇代谢调节中的关键靶点，该抗体为研究原发性高胆固醇血症及相关疾病提供了重要的研究工具。

产品特性

• 产品类型：二抗，特异性识别人源PCSK9蛋白
• 来源宿主：人源化(Humanized)，确保高特异性和亲和力
• 反应性：仅针对人类(Human)PCSK9蛋白
• CAS编号：1407495-04-8
• 生产标准：在无动物成分的严格设施中生产

生产与纯化工艺

该重组生物类似抗体采用先进的体外无蛋白细胞培养技术生产，确保产品无动物源污染。经过多步骤严格纯化过程，包括使用Protein A或G亲和色谱工艺，获得高纯度、低内毒素的抗体产品，为科研实验提供可靠保障。

研究领域与应用

BioSIM 抗人 PCSK9 抗体适用于多种研究场景，特别专注于：

• 原发性高胆固醇血症的分子机制研究
• ELISA实验：用于PCSK9蛋白的定量检测
• FACS分析：用于细胞表面PCSK9表达的研究
• 功能性实验：评估PCSK9在胆固醇代谢通路中的功能
• 体内研究：用于动物模型中的PCSK9相关研究

储存条件

为确保抗体活性和稳定性，请遵循以下储存建议：

• 避免反复冻融，以保持抗体活性
• 短期使用（1-2周）：4°C保存
• 中期储存（最长12个月）：-20°C保存
• 长期储存：-80°C保存

注意事项

关于该抗体的免疫原性信息，请参考随产品附带的技术说明书。建议在使用前进行适当的预实验，以确定最佳实验条件。本产品仅限科研用途，不可用于临床诊断或治疗。

订购信息

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human PCSK9 Antibody (Rampazumab), Biosimilar

Product Overview

BioSIM Anti-Human PCSK9 Antibody (Rampazumab) is a high-quality biosimilar designed specifically for research purposes. This antibody targets the human PCSK9 protein, catalog number SIM0538-1mg, with a specification of 1mg, and is manufactured by InvivoCrown. PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) is a key target in cholesterol metabolism regulation, and this antibody provides an important research tool for studying primary hypercholesterolemia and related diseases.

Product Characteristics

• Product Type: Secondary antibody, specifically recognizes human PCSK9 protein
• Host Origin: Humanized, ensuring high specificity and affinity
• Reactivity: Human PCSK9 protein only
• CAS Number: 1407495-04-8
• Manufacturing Standard: Produced in strict facilities free of animal components

Manufacturing and Purification Process

This recombinant biosimilar antibody is produced using advanced serum-free in vitro cell culture technology to ensure the product is free of animal source contamination. After a multi-step rigorous purification process, including Protein A or G affinity chromatography, a high-purity, low-endotoxin antibody product is obtained, providing reliable assurance for scientific experiments.

Research Fields and Applications

BioSIM Anti-Human PCSK9 Antibody is suitable for various research scenarios, with particular focus on:

• Molecular mechanism studies of primary hypercholesterolemia
• ELISA experiments: for quantitative detection of PCSK9 protein
• FACS analysis: for studying cell surface PCSK9 expression
• Functional assays: to evaluate the function of PCSK9 in cholesterol metabolism pathways
• In vivo studies: for PCSK9-related research in animal models

Storage Conditions

To ensure antibody activity and stability, please follow the storage recommendations below:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term use (1-2 weeks): Store at 4°C
• Medium-term storage (up to 12 months): Store at -20°C
• Long-term storage: Store at -80°C

Precautions

For immunogenicity information about this antibody, please refer to the technical data sheet provided with the product. It is recommended to perform appropriate pre-experiments before use to determine optimal experimental conditions. This product is for research use only and not for clinical diagnosis or treatment.

Ordering Information

Note: The information above may change due to factors such as product optimization and upgrades. Please consult Yacoin Company for specific information.