BioSIM 抗人 PCSK9 抗体 (伯考赛珠单抗)，生物

BioSIM 抗人 PCSK9 抗体 (伯考赛珠单抗)

产品编号：SIM0536-5mg | 供应商：InvivoCrown

产品概述

BioSIM 抗人 PCSK9 抗体是一种高特异性重组人源化抗体，作为伯考赛珠单抗的生物类似药，专为科研用途设计。该抗体采用无动物成分的体外细胞培养技术生产，经过严格的多步骤纯化工艺，确保了高纯度和批次间的一致性，适用于多种基础医学和药物研发应用。

产品特性

• 来源：人源化抗体
• 反应性：仅与人源PCSK9蛋白结合
• 生产技术：无动物成分的体外细胞培养系统
• 纯化工艺：多步骤纯化，包括Protein A/G色谱法
• 规格：5mg/瓶
• CAS号：1407495-02-6

研究领域与应用

该抗体主要应用于原发性高胆固醇血症相关研究，特别适用于以下实验：

• ELISA实验：用于定量检测样本中PCSK9蛋白水平
• FACS分析：可用于流式细胞术研究PCSK在细胞表面的表达与分布
• 功能性分析：评估抗体对PCSK9功能的抑制效果
• 体内研究：在动物模型中研究PCSK9抑制剂的作用机制和效果

技术参数

储存建议

• 短期储存(1-2周)：4°C
• 中期储存(最长12个月)：-20°C
• 长期储存：-80°C
• 注意事项：为确保抗体活性，请避免反复冻融，分装后使用最佳

产品优势

• 无动物成分生产，降低批次间变异和潜在污染风险
• 严格质量控制，确保高特异性和亲和力
• 多种实验验证的应用兼容性
• 适合用于PCSK9相关信号通路研究和药物开发

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human PCSK9 Antibody (Bococizumab)

Catalog Number:SIM0536-5mg | Supplier:InvivoCrown

Product Overview

BioSIM Anti-Human PCSK9 Antibody is a high-specificity recombinant humanized antibody designed as a biosimilar of Bococizumab for research purposes only. This antibody is produced using animal-free in vitro cell culture technology and undergoes rigorous multi-step purification processes to ensure high purity and batch-to-batch consistency, making it suitable for various basic medical research and drug development applications.

Product Characteristics

• Source: Humanized Antibody
• Reactivity: Binds only to human PCSK9 protein
• Production Technology: Animal-free in vitro cell culture system
• Purification: Multi-step purification including Protein A/G chromatography
• Specifications: 5mg/vial
• CAS Number: 1407495-02-6

Research Fields and Applications

This antibody is primarily used in research related to primary hypercholesterolemia and is particularly suitable for the following experiments:

• ELISA: For quantitative detection of PCSK9 protein levels in samples
• FACS Analysis: Can be used for flow cytometry to study the expression and distribution of PCSK9 on the cell surface
• Functional Analysis: To evaluate the inhibitory effect of the antibody on PCSK9 function
• In Vivo Studies: To study the mechanism and effects of PCSK9 inhibitors in animal models

Technical Parameters

Storage Recommendations

• Short-term storage (1-2 weeks): 4°C
• Medium-term storage (up to 12 months): -20°C
• Long-term storage: -80°C
• Note: To maintain antibody activity, avoid repeated freeze-thaw cycles; best to use after aliquoting

Product Advantages

• Animal-free production reduces inter-batch variation and potential contamination risks
• Strict quality control ensures high specificity and affinity
• Compatibility with various experimentally validated applications
• Suitable for PCSK9-related signaling pathway research and drug development

Note: The information above may be subject to change due to product optimization and upgrades. For specific information, please consult Yakeyin Company.