BioSIM 抗人 TREM2 抗体，生物类似药 5mg

BioSIM 抗人 TREM2 抗体，生物类似药，科研用途

产品货号： SIM0515-5mg
产品规格： 5mg
供应商： InvivoCrown
产品类型： 二抗

产品概述

BioSIM anti-Human TREM2 Antibody (AL2p-58 Biosimilar) 是一种高质量的生物类似抗体，专为科研用途设计。该抗体针对触发受体表达在髓样细胞2 (TREM2) 蛋白，该蛋白是近年来神经科学研究领域的热点分子，尤其在阿尔茨海默病等神经退行性疾病研究中具有重要意义。

生产与纯化工艺

该重组生物类似抗体在严格的无动物成分生产设施中制造，采用先进的体外无蛋白细胞培养技术，确保了产品的纯度和一致性。经过多步骤精细纯化工艺，包括专有的Protein A或G色谱技术，能够高效去除杂质，获得高特异性和高亲和力的抗体产品。这种生产方式不仅避免了动物源性成分的潜在污染风险，还大大提高了批次间的一致性和可靠性。

研究领域与应用

主要研究领域： 阿尔茨海默病及其他神经退行性疾病

应用类型：

• ELISA： 适用于TREM2蛋白的定量检测，可用于样本中TREM2表达水平的精确测定
• FACS： 用于流式细胞术分析，可识别和量化表达TREM2的细胞群体
• Functional assay： 功能性分析研究，评估TREM2在细胞信号传导中的生物学功能
• Research in vivo： 适用于体内研究，探索TREM2在动物模型中的功能和调控机制

技术参数

免疫原： 请参考产品说明书获取详细信息

来源宿主： Human

反应性： Human

储存建议

为确保抗体活性和稳定性，请遵循以下储存条件：

• 避免反复冻融，以保持抗体活性
• 短期储存（1-2周）： 4°C
• 中期储存（最长12个月）： -20°C
• 长期储存： -80°C

科研应用价值

TREM2作为小胶质细胞表面的一种重要受体，在神经炎症反应和阿尔茨海默病病理过程中扮演关键角色。本抗体为研究人员提供了一种可靠的研究工具，可用于探索TREM2在神经退行性疾病中的分子机制，为相关疾病的诊断和治疗靶点发现提供支持。

实验设计建议

在使用本抗体进行实验时，建议：

• 根据具体应用优化抗体稀释比例
• 设置适当的阳性对照和阴性对照
• 结合多种实验方法验证结果的可靠性

本产品仅限科研使用，不可用于临床诊断或治疗。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human TREM2 Antibody, Biosimilar, for Research Use

Product Code: SIM0515-5mg
Product Specification: 5mg
Supplier: InvivoCrown
Product Type: Secondary Antibody

Product Overview

BioSIM anti-Human TREM2 Antibody (AL2p-58 Biosimilar) is a high-quality biosimilar antibody designed specifically for research purposes. This antibody targets the Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein, which has become a molecule of significant interest in neuroscience research in recent years, particularly in the study of neurodegenerative diseases such as Alzheimer's disease.

Production and Purification Process

This recombinant biosimilar antibody is manufactured in strict animal-component-free production facilities using advanced animal-free protein-free cell culture technology to ensure product purity and consistency. Through a multi-step fine purification process, including proprietary Protein A or G chromatography technology, impurities are efficiently removed to obtain antibody products with high specificity and high affinity. This production method not only avoids potential contamination risks from animal-derived components but also significantly improves inter-batch consistency and reliability.

Research Areas and Applications

Main Research Areas: Alzheimer's disease and other neurodegenerative diseases

Application Types:

• ELISA: Suitable for quantitative detection of TREM2 protein, can be used for precise determination of TREM2 expression levels in samples
• FACS: Used for flow cytometry analysis, can identify and quantify cell populations expressing TREM2
• Functional assay: Functional analysis research to evaluate the biological function of TREM2 in cell signaling
• Research in vivo: Suitable for in vivo research to explore the function and regulatory mechanisms of TREM2 in animal models

Technical Parameters

Immunogen: Please refer to the product manual for detailed information

Source Host: Human

Reactivity: Human

Storage Recommendations

To ensure antibody activity and stability, please follow the following storage conditions:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term storage (1-2 weeks): 4°C
• Medium-term storage (up to 12 months): -20°C
• Long-term storage: -80°C

Research Application Value

As an important receptor on the surface of microglia, TREM2 plays a key role in neuroinflammatory responses and the pathological process of Alzheimer's disease. This antibody provides researchers with a reliable research tool for exploring the molecular mechanisms of TREM2 in neurodegenerative diseases, supporting the discovery of diagnostic and therapeutic targets for related diseases.

Experimental Design Recommendations

When using this antibody for experiments, it is recommended to:

• Optimize antibody dilution ratios according to specific applications
• Set appropriate positive and negative controls
• Combine multiple experimental methods to verify the reliability of results

This product is limited to research use only and is not for clinical diagnosis or treatment.

Note: The above information may change due to factors such as product optimization and upgrading. For specific information, please consult Yaokein Company.