BioSIM 抗人 HTRA1 抗体 (戈莱恩尼单抗)，生物

BioSIM 抗人 HTRA1 抗体 (戈莱恩尼单抗)，生物类似药

产品概述

产品名称：BioSIM anti-Human HTRA1 Antibody (Galegenimab Biosimilar), Research Grade

中文名称：BioSIM 抗人 HTRA1 抗体 (戈莱恩尼单抗)，生物类似药，科研用途 [ CAS: 2403683-24-7]

产品类型：二抗

供应商：InvivoCrown

产品货号：SIM0502-5mg

产品规格：5mg

产品特性

来源宿主：Humanized（人源化）

反应性：Human（人源）

研究领域：地图状萎缩，年龄相关性黄斑变性

应用类型：ELISA, FACS, Functional assay, Research in vivo

背景信息

戈莱恩尼单抗是一种针对HTRA1（丝氨酸蛋白酶1）的人源化单克隆抗体。HTRA1是一种在多种组织中表达的蛋白酶，其在眼部疾病特别是年龄相关性黄斑变性和地图状萎缩的病理过程中发挥重要作用。

该重组生物类似抗体在严格的无动物成分设施中生产，采用体外无蛋白细胞培养技术，确保了产品的高纯度和批次一致性。经过多步骤的纯化过程，包括Protein A或G色谱工艺，有效去除杂质，提高抗体特异性和活性。

技术参数

• 免疫原：详细免疫原信息请参考产品说明书
• 纯度：经多步纯化工艺处理
• 生产条件：无动物成分，无蛋白细胞培养

储存条件

为确保抗体活性稳定，请遵循以下储存建议：

• 短期储存（1-2周）：4°C
• 中期储存（最长12个月）：-20°C
• 长期储存：-80°C
• 注意事项：请避免反复冻融，以免影响抗体活性

应用领域

该抗体适用于多种科研应用，包括：

• ELISA：用于HTRA1蛋白的定量检测
• FACS：用于细胞表面HTRA1表达的流式细胞术分析
• 功能性实验：研究HTRA1在细胞信号通路中的作用
• 体内研究：用于动物模型中HTRA1相关疾病的机制研究

产品优势

• 高特异性：针对人源HTRA1蛋白，减少交叉反应
• 批次一致性：严格的生产工艺确保批次间差异最小化
• 多种应用：适用于多种实验平台和研究需求
• 无动物成分：降低潜在污染风险，提高实验可靠性

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human HTRA1 Antibody (Galegenimab Biosimilar)

Product Overview

Product Name:BioSIM anti-Human HTRA1 Antibody (Galegenimab Biosimilar), Research Grade

Chinese Name:BioSIM anti-Human HTRA1 Antibody (Galegenimab Biosimilar), Research Use [ CAS: 2403683-24-7]

Product Type:Secondary Antibody

Supplier:InvivoCrown

Catalog Number:SIM0502-5mg

Product Specification:5mg

Product Characteristics

Host:Humanized

Reactivity:Human

Research Areas:Geographic Atrophy, Age-related Macular Degeneration

Application Types:ELISA, FACS, Functional assay, Research in vivo

Background Information

Galegenimab is a humanized monoclonal antibody targeting HTRA1 (Serine Peptidase 1). HTRA1 is a protease expressed in various tissues and plays an important role in the pathological processes of eye diseases, particularly age-related macular degeneration and geographic atrophy.

This recombinant biosimilar antibody is produced in strict animal-free facilities using in vitro protein-free cell culture technology, ensuring high purity and batch consistency. After a multi-step purification process including Protein A or G chromatography, impurities are effectively removed to enhance antibody specificity and activity.

Technical Parameters

• Immunogen:For detailed immunogen information, please refer to the product manual
• Purity:Processed by multi-step purification process
• Production Conditions:Animal-free, protein-free cell culture

Storage Conditions

To ensure antibody activity stability, please follow the following storage recommendations:

• Short-term storage (1-2 weeks):4°C
• Medium-term storage (up to 12 months):-20°C
• Long-term storage:-80°C
• Precautions:Please avoid repeated freeze-thaw cycles to prevent affecting antibody activity

Application Areas

This antibody is suitable for various research applications, including:

• ELISA:For quantitative detection of HTRA1 protein
• FACS:For flow cytometry analysis of cell surface HTRA1 expression
• Functional assays:For studying the role of HTRA1 in cellular signaling pathways
• In vivo research:For mechanistic studies of HTRA1-related diseases in animal models

Product Advantages

• High specificity: Targets human HTRA1 protein, reducing cross-reactivity
• Batch consistency: Strict production process ensures minimal inter-batch differences
• Multiple applications: Suitable for various experimental platforms and research needs
• Animal-free: Reduces potential contamination risks and improves experimental reliability

Note: The above information may change due to product optimization and upgrading. For specific information, please consult Yaokein Company.