BioSIM 抗人 SIGLEC8 抗体 (莱瑞利单抗)，生

BioSIM 抗人 SIGLEC8 抗体 (莱瑞利单抗)，生物类似药

产品基本信息

英文名称：BioSIM anti-Human SIGLEC8 Antibody (Lirentelimab Biosimilar), Research Grade

中文名称：BioSIM 抗人 SIGLEC8 抗体 (莱瑞利单抗)，生物类似药，科研用途 [CAS: 2283348-97-8]

产品类型：二抗

供应商：InvivoCrown

产品货号：SIM0412-5mg

产品规格：5mg

产品概述

BioSIM 抗人 SIGLEC8 抗体是一种高特异性的人源化抗体，作为莱瑞利单抗的生物类似药，专为科研用途设计。该抗体靶向人类SIGLEC8蛋白，在免疫学研究领域具有广泛的应用价值，特别是在嗜酸性胃炎和十二指肠炎等疾病的研究中表现出色。

技术特点与优势

• 生产技术：在无动物成分的设施中生产，确保产品的高纯度和低污染风险
• 细胞培养：采用无蛋白细胞培养技术，减少潜在的外源蛋白干扰
• 纯化工艺：经过多步骤纯化过程，包括Protein A或G色谱工艺，确保抗体的高纯度和特异性
• 来源宿主：人源化设计，提高与人类靶点的结合亲和力
• 反应性：特异性识别人类SIGLEC8蛋白

研究领域与应用

BioSIM 抗人 SIGLEC8 抗体适用于多种科研应用：

• ELISA：可用于检测样本中SIGLEC8蛋白的表达水平
• FACS：适用于流式细胞术，分析细胞表面SIGLEC8的表达情况
• Functional assay：可用于评估SIGLEC8在细胞功能中的作用机制
• Research in vivo：适用于动物模型研究，探索SIGLEC8在体内的生物学功能

重点研究领域：嗜酸性胃炎、十二指肠炎等与嗜酸性粒细胞相关的炎症性疾病

产品规格与保存条件

产品规格：5mg/支

保存建议：

• 避免反复冻融，以保持抗体活性
• 短期需求（1-2周）：4°C保存
• 中期储存（最长12个月）：-20°C保存
• 长期储存：-80°C保存

使用说明

该抗体专为科研用途设计，具体使用方法请参考产品说明书。免疫原性信息请查阅相关技术文档。建议在使用前进行适当的滴度优化，以确保最佳实验结果。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human SIGLEC8 Antibody (Lirentelimab Biosimilar), Research Grade

Product Basic Information

English Name: BioSIM anti-Human SIGLEC8 Antibody (Lirentelimab Biosimilar), Research Grade

Chinese Name: BioSIM anti-Human SIGLEC8 Antibody (Lirentelimab Biosimilar), for Research Use [CAS: 2283348-97-8]

Product Type: Secondary Antibody

Supplier: InvivoCrown

Product Code: SIM0412-5mg

Product Specification: 5mg

Product Overview

BioSIM anti-Human SIGLEC8 Antibody is a highly specific humanized antibody, developed as a biosimilar of Lirentelimab and designed specifically for research purposes. This antibody targets the human SIGLEC8 protein and has broad application value in immunology research, particularly demonstrating excellent performance in the study of diseases such as eosinophilic gastritis and duodenitis.

Technical Features and Advantages

• Production Technology: Produced in animal component-free facilities to ensure high purity and low contamination risk
• Cell Culture: Utilizes protein-free cell culture technology to minimize potential interference from exogenous proteins
• Purification Process: Undergoes a multi-step purification process, including Protein A or G chromatography, to ensure high purity and specificity of the antibody
• Source Host: Humanized design to improve binding affinity to human targets
• Reactivity: Specifically recognizes human SIGLEC8 protein

Research Fields and Applications

BioSIM anti-Human SIGLEC8 Antibody is suitable for various research applications:

• ELISA: Can be used to detect the expression level of SIGLEC8 protein in samples
• FACS: Suitable for flow cytometry to analyze the expression of SIGLEC8 on the cell surface
• Functional assay: Can be used to evaluate the mechanism of action of SIGLEC8 in cell functions
• Research in vivo: Suitable for animal model studies to explore the biological functions of SIGLEC8 in vivo

Key Research Areas: Eosinophilic gastritis, duodenitis, and other eosinophil-related inflammatory diseases

Product Specifications and Storage Conditions

Product Specification: 5mg/vial

Storage Recommendations:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term needs (1-2 weeks): Store at 4°C
• Medium-term storage (up to 12 months): Store at -20°C
• Long-term storage: Store at -80°C

Instructions for Use

This antibody is designed for research purposes only. Please refer to the product manual for specific usage instructions. Please refer to relevant technical documentation for immunogenicity information. It is recommended to perform appropriate titer optimization before use to ensure optimal experimental results.

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yaokein Company.