BioSIM 抗人 TYRP1 抗体 (法兰妥单抗)，生物类

BioSIM 抗人 TYRP1 抗体 (法兰妥单抗) 生物类似药 科研用途

产品概述

本产品为InvivoCrown推出的BioSIM系列抗人TYRP1抗体，对应生物类似药为法兰妥单抗（Flanvotumab），仅用于科研领域，不可用于临床诊断或治疗。

基本信息

• 英文名称：BioSIM anti-Human TYRP1 Antibody (Flanvotumab Biosimilar), Research Grade
• 中文名称：BioSIM 抗人 TYRP1 抗体 (法兰妥单抗)，生物类似药，科研用途
• CAS号：1188277-05-5
• 产品类型：二抗
• 供应商：InvivoCrown
• 产品货号：SIM0219-5mg
• 产品规格：5mg/支
• 来源宿主：Human（人源）
• 反应性：Human（仅识别人源TYRP1抗原）

背景与生产工艺

法兰妥单抗（Flanvotumab）为靶向TYRP1的重组抗体，本产品作为其生物类似药，生产工艺遵循严格科研级标准：

• 生产设施无动物成分污染风险，全程采用体外无蛋白细胞培养技术；
• 经多步骤纯化工艺，包含Protein A或G亲和色谱等关键步骤，确保抗体纯度与活性；
• 产品符合科研抗体的基础质量控制要求，可稳定用于后续实验研究。

研究领域与应用

核心研究领域

黑色素瘤（TYRP1为黑色素瘤细胞表面关键标志物，本抗体可用于相关机制、靶点验证及治疗潜力研究）

适用实验类型

• 酶联免疫吸附实验（ELISA）
• 荧光激活细胞分选（FACS）
• 功能学实验（Functional assay）
• 体内研究（Research in vivo）

免疫原信息

本抗体的具体免疫原序列、来源及相关特性请参照产品附带的详细说明书，建议实验前仔细阅读以匹配实验设计需求。

保存建议

为维持抗体活性与稳定性，需严格遵循以下储存条件：

• 短期使用（1-2周）：4℃避光密封保存，避免反复冻融；
• 中期储存（最长12个月）：-20℃低温冰箱中保存，建议分装为小体积（如100μL/管）避免多次冻融；
• 长期储存（超过12个月）：-80℃超低温冰箱中保存，分装后可长期稳定；
• 注意：实验前取出所需体积，剩余样品立即放回对应温度储存，不可室温长时间放置。

注意事项

• 本产品仅用于科研用途，不可用于人体、动物临床诊断或治疗；
• 使用前建议短暂离心（如10000rpm×1min），避免运输过程中产生的沉淀影响实验结果；
• 实验操作需遵循实验室生物安全规范，避免交叉污染；
• 若发现产品出现浑浊、明显沉淀或活性下降（可通过预实验验证），请勿继续使用。

供应商支持

InvivoCrown提供本产品的技术咨询与实验方案建议，如需进一步获取说明书、COA（分析报告）等资料，可联系供应商获取。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human TYRP1 Antibody (Flanvotumab Biosimilar) for Research Use

Product Overview

This product is an anti-human TYRP1 antibody from the BioSIM Series launched by InvivoCrown, corresponding to the biosimilar of Flanvotumab. It is for research use only and not intended for clinical diagnosis or treatment.

Basic Information

• English Name：BioSIM anti-Human TYRP1 Antibody (Flanvotumab Biosimilar), Research Grade
• Chinese Name：BioSIM 抗人 TYRP1 抗体 (法兰妥单抗)，生物类似药，科研用途
• CAS No.：1188277-05-5
• Product Type：Secondary Antibody
• Supplier：InvivoCrown
• Catalog No.：SIM0219-5mg
• Specification：5mg/vial
• Host Source：Human
• Reactivity：Human (only recognizes human TYRP1 antigen)

Background and Production Process

Flanvotumab is a recombinant antibody targeting TYRP1. As its biosimilar, this product is manufactured under strict research-grade standards:

• No risk of animal-derived component contamination in production facilities; animal-free protein-free cell culture technology is used throughout the process;
• Subjected to multi-step purification processes, including key steps such as Protein A or G affinity chromatography, to ensure antibody purity and activity;
• The product meets the basic quality control requirements for research antibodies and can be stably used in subsequent experimental studies.

Research Areas and Applications

Core Research Areas

Melanoma (TYRP1 is a key marker on the surface of melanoma cells; this antibody can be used for studies on related mechanisms, target validation, and therapeutic potential)

Applicable Experimental Types

• Enzyme-Linked Immunosorbent Assay (ELISA)
• Fluorescence-Activated Cell Sorting (FACS)
• Functional Assay
• In Vivo Research

Immunogen Information

Please refer to the detailed product manual for the specific immunogen sequence, source, and related characteristics of this antibody. It is recommended to read it carefully before experiments to match experimental design requirements.

Storage Recommendations

To maintain antibody activity and stability, strictly follow the following storage conditions:

• Short-term use (1-2 weeks)：Store at 4℃ in the dark and sealed; avoid repeated freeze-thaw cycles;
• Medium-term storage (up to 12 months)：Store in a -20℃ freezer; it is recommended to aliquot into small volumes (e.g., 100μL/tube) to avoid multiple freeze-thaw cycles;
• Long-term storage (more than 12 months)：Store in a -80℃ ultra-low temperature freezer; it can be stable for a long time after aliquoting;
• Note：Take out the required volume before experiments; immediately return the remaining sample to storage at the corresponding temperature; do not leave it at room temperature for a long time.

Precautions

• This product is for research use only and not intended for clinical diagnosis or treatment of humans or animals;
• It is recommended to centrifuge briefly (e.g., 10000 rpm × 1 min) before use to avoid precipitation generated during transportation from affecting experimental results;
• Laboratory operations must follow biosafety regulations to avoid cross-contamination;
• If the product is found to be turbid, have obvious precipitation, or show decreased activity (verifiable by pre-experiments), do not continue to use it.

Supplier Support

InvivoCrown provides technical consultation and experimental protocol suggestions for this product. If you need further information such as the manual or COA (Certificate of Analysis), please contact the supplier.

Note: The above information may change due to product optimization, upgrading, and other factors. For specific information, please consult InvivoCrown.