BioSIM 抗人 C5aR1 抗体 (艾朵利单抗)，生物类

BioSIM 抗人 C5aR1 抗体 (艾朵利单抗) 生物类似药 - 科研用途

一、核心基本信息

英文名称：BioSIM anti-Human C5aR1 Antibody (Avdoralimab Biosimilar), Research Grade

中文名称：BioSIM 抗人 C5aR1 抗体 (艾朵利单抗)，生物类似药，科研用途

CAS号：2226393-85-5

产品类型：二抗

供应商：InvivoCrown

产品货号：SIM0105-5mg

产品规格：5mg

二、产品背景与生产工艺

该重组生物类似抗体为艾朵利单抗（Avdoralimab）的科研级参照品，生产过程遵循高纯度制备标准：

• 生产环境为无动物成分的封闭设施，避免外源性污染物引入
• 仅采用体外无蛋白细胞培养技术进行表达，减少非特异性干扰
• 经多步骤纯化工艺精制，核心环节包含Protein A/G亲和色谱分离

三、研究应用与领域

聚焦研究领域：实体瘤、类风湿性关节炎（C5aR1通路相关疾病研究）

适用实验类型：

• 酶联免疫吸附实验（ELISA）
• 荧光激活细胞分选（FACS）
• 功能学活性实验（Functional assay）
• 体内动物模型研究（Research in vivo）

四、免疫学特性

免疫原信息：请参考产品配套说明书（含免疫原序列/来源细节）

来源宿主：Human（人源化重组抗体）

抗原反应性：Human（特异性识别人源C5aR1抗原）

五、保存与稳定性建议

为维持抗体活性及稳定性，需严格遵循以下储存条件：

• 短期使用（1-2周）：4°C避光保存（避免反复冻融）
• 中期储存（最长12个月）：-20°C避光保存（建议分装为小体积）
• 长期储存（＞12个月）：-80°C避光保存（分装后减少冻融次数）

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human C5aR1 Antibody (Avdoralimab) Biosimilar - For Research Use

I. Core Basic Information

English Name: BioSIM anti-Human C5aR1 Antibody (Avdoralimab Biosimilar), Research Grade

Chinese Name: BioSIM Anti-Human C5aR1 Antibody (Avdoralimab), Biosimilar, Research Use

CAS Number: 2226393-85-5

Product Type: Secondary Antibody

Supplier: InvivoCrown

Catalog Number: SIM0105-5mg

Size: 5mg

II. Product Background and Manufacturing Process

This recombinant biosimilar antibody is a research-grade reference standard for Avdoralimab, manufactured following high-purity preparation standards:

• Produced in a closed facility free of animal components to prevent introduction of exogenous contaminants
• Expressed using only in vitro protein-free cell culture technology to reduce non-specific interference
• Purified through a multi-step purification process, with core steps including Protein A/G affinity chromatography separation

III. Research Applications and Fields

Research Focus Areas: Solid tumors, rheumatoid arthritis (research on C5aR1 pathway-related diseases)

Suitable Experimental Types:

• Enzyme-Linked Immunosorbent Assay (ELISA)
• Fluorescence-Activated Cell Sorting (FACS)
• Functional Activity Assay
• In vivo Animal Model Research

IV. Immunological Characteristics

Immunogen Information: Please refer to the accompanying product manual (includes immunogen sequence/source details)

Source Host: Human (humanized recombinant antibody)

Antigen Reactivity: Human (specifically recognizes human C5aR1 antigen)

V. Storage and Stability Recommendations

To maintain antibody activity and stability, strictly follow the storage conditions below:

• Short-term use (1-2 weeks): Store at 4°C protected from light (avoid repeated freeze-thaw cycles)
• Medium-term storage (up to 12 months): Store at -20°C protected from light (aliquoting into small volumes is recommended)
• Long-term storage (>12 months): Store at -80°C protected from light (aliquot to reduce freeze-thaw cycles)

Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please contact InvivoCrown.