BioSIM 抗人 CD30 抗体 (伊妥木单抗)，生物类似

产品基本信息

英文名称：BioSIM anti-Human CD30 Antibody (Iratumumab Biosimilar), Research Grade

中文名称：BioSIM 抗人 CD30 抗体 (伊妥木单抗)，生物类似药，科研用途 [ CAS: 640735-09-7]

产品类型：二抗

供应商：InvivoCrown

产品货号：SIM0102-5mg

产品规格：5mg

背景资料与生产工艺

核心背景：该产品为伊妥木单抗的生物类似抗体，仅用于科研用途。

生产工艺细节：

• 生产环境：于无动物成分的设施中生产，降低外源性动物源污染物引入风险
• 培养技术：采用体外无蛋白细胞培养技术，减少杂蛋白干扰，提升产品纯度
• 纯化工艺：经多步骤纯化流程，包含Protein A或G色谱工艺（利用Protein A/G对抗体Fc段的高亲和力，实现目标抗体高效富集与纯化）

研究领域

重点研究方向：

• 原发性皮肤间变性大细胞淋巴瘤
• 难治性霍奇金淋巴瘤

应用类型

可应用场景：

• ELISA（酶联免疫吸附实验）
• FACS（荧光激活细胞分选）
• Functional assay（功能实验）
• Research in vivo（体内研究）

免疫原与来源

免疫原说明：具体免疫原信息请参考产品说明书

来源宿主：Human（人源）

反应性：Human（仅识别人源CD30抗原）

保存建议

关键注意事项：避免反复冻融（反复冻融会导致抗体空间结构破坏，影响生物活性）

不同周期储存条件：

• 短期需求（1-2周）：4°C环境下保存
• 中期储存（最长12个月）：-20°C环境下保存
• 长期储存：-80°C环境下保存

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Product Basic Information

English Name: BioSIM anti-Human CD30 Antibody (Iratumumab Biosimilar), Research Grade

Chinese Name: BioSIM anti-Human CD30 Antibody (Iratumumab), Biosimilar, Research Use [CAS: 640735-09-7]

Product Type: Secondary Antibody

Supplier: InvivoCrown

Catalog Number: SIM0102-5mg

Size: 5mg

Background and Production Process

Core Background: This product is a biosimilar antibody of Iratumumab, for research use only.

Production Process Details:

• Production Environment: Manufactured in animal-component-free facilities to reduce the risk of introducing exogenous animal-derived contaminants
• Culture Technology: Utilizes protein-free in vitro cell culture technology to reduce interference from contaminating proteins and improve product purity
• Purification Process: Undergoes multi-step purification process, including Protein A or G chromatography (leveraging the high affinity of Protein A/G for the Fc region of antibodies to achieve efficient enrichment and purification of target antibodies)

Research Fields

Key Research Areas:

• Primary Cutaneous Anaplastic Large Cell Lymphoma
• Refractory Hodgkin's Lymphoma

Application Types

Applicable Scenarios:

• ELISA (Enzyme-Linked Immunosorbent Assay)
• FACS (Fluorescence-Activated Cell Sorting)
• Functional assay
• Research in vivo

Immunogen and Source

Immunogen Description: For specific immunogen information, please refer to the product manual

Source Host: Human

Reactivity: Human (Recognizes human CD30 antigen only)

Storage Recommendations

Key Precautions: Avoid repeated freeze-thaw cycles (repeated freeze-thaw cycles may lead to disruption of antibody spatial structure, affecting biological activity)

Storage Conditions for Different Periods:

• Short-term storage (1-2 weeks): Store at 4°C
• Medium-term storage (up to 12 months): Store at -20°C
• Long-term storage: Store at -80°C

Note: The above information may be subject to change due to factors such as product optimization and upgrades. For specific information, please contact InvivoCrown.