BioSIM 抗猫 NGF 抗体 (夫卢维单抗)，生物类似药

BioSIM 抗猫 NGF 抗体 (夫卢维单抗) 生物类似药（科研用途）

产品核心信息

• 英文名称：BioSIM anti-Cat NGF Antibody (Frunevetmab Biosimilar), Research Grade
• 中文名称：BioSIM 抗猫 NGF 抗体 (夫卢维单抗)，生物类似药，科研用途 [ CAS: 1708936-80-4 ]
• 供应商：InvivoCrown
• 产品货号：SIM0085-5mg
• 产品规格：5mg/支
• 产品类型：二抗

关键参数详情

背景与生产工艺

本产品为夫卢维单抗（Frunevetmab）的生物类似药，靶向猫神经生长因子（NGF），聚焦猫骨关节炎（OA）相关科研研究。

生产工艺遵循严格科研级标准：

• 在无动物成分的设施中生产，降低异源污染物引入风险；
• 采用体外无蛋白细胞培养技术，避免培养基蛋白杂质干扰实验结果；
• 经多步骤纯化工艺（含Protein A/G色谱环节），提升抗体纯度与特异性。

研究应用方向

核心研究领域

猫骨关节炎（OA）：NGF是OA疼痛通路关键因子，本抗体可用于OA疼痛机制、病理进程的基础研究。

适用实验类型

• ELISA：猫NGF定量检测，辅助OA生物标志物分析；
• FACS：表达NGF的猫细胞亚群分选与表型鉴定；
• Functional assay（功能实验）：验证抗体对猫NGF功能的调控效果；
• Research in vivo（体内研究）：猫模型体内实验，探索NGF在OA中的作用机制。

保存与稳定性建议

为维持抗体活性，需严格遵循以下储存条件：

• 短期使用（1-2周）：4°C避光保存（避免反复冻融）；
• 中短期储存（≤12个月）：-20°C避光保存（建议分装为小体积）；
• 长期储存（＞12个月）：-80°C避光保存（分装后可稳定保持活性）；
• 注意事项：严禁反复冻融，取用后立即放回对应温度环境。

产品声明

本产品仅用于科研用途，不用于临床诊断、治疗或人体/动物体内直接应用，请严格遵守实验室使用规范。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Cat NGF Antibody (Frunevetmab) Biosimilar (Research Use)

Core Product Information

• English Name: BioSIM anti-Cat NGF Antibody (Frunevetmab Biosimilar), Research Grade
• Chinese Name: BioSIM anti-Cat NGF Antibody (Frunevetmab), Biosimilar, Research Use [CAS: 1708936-80-4]
• Supplier: InvivoCrown
• Catalog Number: SIM0085-5mg
• Size: 5mg/vial
• Product Type: Secondary Antibody

Detailed Key Parameters

Background and Production Process

This product is a biosimilar of Frunevetmab, targeting cat Nerve Growth Factor (NGF), focusing on research related to feline osteoarthritis (OA).

The production process follows strict research-grade standards:

• Produced in animal component-free facilities to reduce the risk of introducing xenogeneic contaminants;
• Utilizes in vitro protein-free cell culture technology to avoid interference from culture medium protein impurities in experimental results;
• Undergoes multi-step purification process (including Protein A/G chromatography) to enhance antibody purity and specificity.

Research Applications

Core Research Areas

Feline Osteoarthritis (OA): NGF is a key factor in OA pain pathways. This antibody can be used for basic research on OA pain mechanisms and pathological processes.

Applicable Experimental Types

• ELISA: Quantitative detection of feline NGF, assisting in OA biomarker analysis;
• FACS: Sorting and phenotypic identification of feline cell subpopulations expressing NGF;
• Functional assay: Verification of the regulatory effect of the antibody on feline NGF function;
• Research in vivo: In vivo experiments in feline models to explore the mechanism of NGF in OA.

Storage and Stability Recommendations

To maintain antibody activity, strictly follow the storage conditions below:

• Short-term use (1-2 weeks): Store at 4°C protected from light (avoid repeated freeze-thaw cycles);
• Medium to short-term storage (≤12 months): Store at -20°C protected from light (aliquoting into small volumes is recommended);
• Long-term storage (>12 months): Store at -80°C protected from light (activity can be stably maintained after aliquoting);
• Precautions: Avoid repeated freeze-thaw cycles. Return to the corresponding temperature environment immediately after use.

Product Statement

This product is intended for research use only, not for clinical diagnosis, treatment, or direct in vivo application in humans/animals. Please strictly adhere to laboratory usage guidelines.

Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please contact InvivoCrown.