BioSIM 抗人 CD30 抗体 (维布妥昔单抗)，生物类

BioSIM 抗人 CD30 抗体（维布妥昔单抗生物类似药）- 科研级

产品基本信息

• 英文名称：BioSIM anti-Human CD30 Antibody (Brentuximab Biosimilar), Research Grade
• 中文名称：BioSIM 抗人 CD30 抗体（维布妥昔单抗），生物类似药，科研用途
• CAS号：914088-09-8、2088770-90-3
• 供应商：InvivoCrown
• 产品货号：SIM0101-1mg
• 产品规格：1mg
• 产品类型：二抗

产品背景资料

本产品为维布妥昔单抗（Brentuximab）的非治疗性生物类似药，其可变区序列与临床用靶向CD30的人源化IgG1单克隆抗体完全一致。

CD30是一种分子量为120 kDa的糖蛋白，主要表达于CD8⁺/CD4⁺淋巴细胞、嗜酸性粒细胞等细胞表面，外周血中无表达，因此是淋巴瘤等疾病研究的理想靶点。

临床用Brentuximab作为BV ADC（抗体药物偶联物）的核心抗体，可将微管抑制剂MMAE精准递送至CD30⁺癌细胞，在霍奇金淋巴瘤（HL）、系统性间变性大细胞淋巴瘤（sALCL）、外周T细胞淋巴瘤（PTCL）等疾病研究中具有明确应用价值。

重点研究领域：霍奇金淋巴瘤（HL）、系统性间变性大细胞淋巴瘤（ALCL）

应用类型

• 酶联免疫吸附实验（ELISA）
• 荧光激活细胞分选（FACS）
• 细胞功能实验（Functional assay）
• 体内研究（Research in vivo）

免疫原与来源

• 免疫原：请参考产品配套说明书
• 来源宿主：嵌合型（Chimeric）

反应性

本产品特异性识别人源（Human）CD30抗原

保存建议

• 为维持产品活性，严禁反复冻融
• 短期使用（1-2周）：4°C避光保存
• 中期储存（最长12个月）：-20°C避光保存
• 长期储存：-80°C避光保存

注意事项

本产品仅用于科研用途，不用于临床诊断、治疗或人体试验，也不用于食品、化妆品、兽药等领域。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human CD30 Antibody (Brentuximab Biosimilar) - Research Grade

Basic Product Information

• English Name: BioSIM anti-Human CD30 Antibody (Brentuximab Biosimilar), Research Grade
• Chinese Name: BioSIM anti-Human CD30 Antibody (Brentuximab), Biosimilar, Research Use
• CAS Number: 914088-09-8, 2088770-90-3
• Supplier: InvivoCrown
• Catalog Number: SIM0101-1mg
• Size: 1mg
• Product Type: Secondary Antibody

Product Background

This product is a non-therapeutic biosimilar of Brentuximab, with a variable region sequence identical to the clinically used humanized IgG1 monoclonal antibody targeting CD30.

CD30 is a 120 kDa glycoprotein primarily expressed on the surface of CD8⁺/CD4⁺ lymphocytes, eosinophils, and other cells, with no expression in peripheral blood, making it an ideal target for lymphoma research.

Clinical Brentuximab serves as the core antibody in BV ADC (Antibody-Drug Conjugate), precisely delivering the microtubule inhibitor MMAE to CD30⁺ cancer cells, demonstrating clear application value in research on Hodgkin lymphoma (HL), systemic anaplastic large cell lymphoma (sALCL), peripheral T-cell lymphoma (PTCL), and other diseases.

Key Research Areas: Hodgkin Lymphoma (HL), Systemic Anaplastic Large Cell Lymphoma (ALCL)

Applications

• Enzyme-Linked Immunosorbent Assay (ELISA)
• Fluorescence-Activated Cell Sorting (FACS)
• Functional Assay
• In Vivo Research

Immunogen and Source

• Immunogen: Please refer to the product manual
• Source Host: Chimeric

Reactivity

This product specifically recognizes Human CD30 antigen

Storage Recommendations

• To maintain product activity, repeated freeze-thaw cycles are strictly prohibited
• Short-term use (1-2 weeks): Store at 4°C protected from light
• Medium-term storage (up to 12 months): Store at -20°C protected from light
• Long-term storage: Store at -80°C protected from light

Precautions

This product is for research use only and is not intended for clinical diagnosis, treatment, or human trials, nor for use in food, cosmetics, veterinary medicine, or other fields.

Note: The above information may be subject to change due to product optimization and upgrades. Please contact InvivoCrown for specific information.