BioSIM 抗人 CD22 抗体，生物类似药 1mg

BioSIM 抗人 CD22 抗体（NCI-m971 生物类似药，科研级）

产品基本信息

• 英文全称：BioSIM anti-Human CD22 Antibody (NCI-m971 Biosimilar), Research Grade
• 中文全称：BioSIM 抗人 CD22 抗体（NCI-m971 生物类似药，科研用途）
• 供应商：InvivoCrown
• 产品货号：SIM0094-1mg
• 产品规格：1mg/支
• 产品类型：二抗

生产工艺与背景

该抗体为针对人CD22的重组生物类似药，采用体外无蛋白细胞培养技术制备，全程在无动物成分的生产设施中完成，有效规避外源性动物源蛋白污染风险。

生产流程包含多步骤纯化工艺，其中关键步骤采用Protein A或G亲和色谱技术，确保抗体纯度与生物活性的稳定性，符合科研级产品的质量要求。

研究领域与应用场景

核心研究方向

急性淋巴细胞白血病（ALL）：CD22作为B淋巴细胞表面特异性糖蛋白，在B系急性淋巴细胞白血病细胞中高表达，是该领域的重要研究靶点。

适用应用类型

• ELISA：可用于定量检测样本中人CD22蛋白的表达水平；
• FACS（流式细胞术）：适用于分析人源细胞群体中CD22阳性细胞的比例与表型特征；
• Functional Assay（功能实验）：可用于研究CD22相关的细胞信号通路或功能活性；
• Research in vivo（体内研究）：支持动物模型中的相关基础研究（需遵循科研伦理规范）。

免疫学特性

• 来源宿主：人源化（Humanized）；
• 反应性：仅针对人（Human）CD22抗原；
• 免疫原：具体信息请参考产品附带说明书。

保存与运输建议

注意事项：为维持抗体活性，需避免反复冻融循环。

• 短期保存（1-2周）：4°C避光保存；
• 中短期保存（最长12个月）：-20°C避光保存（建议分装为小体积，减少冻融次数）；
• 长期保存：-80°C避光保存（分装后可长期维持活性）。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human CD22 Antibody (NCI-m971 Biosimilar, Research Grade)

Product Basic Information

• English Full Name: BioSIM anti-Human CD22 Antibody (NCI-m971 Biosimilar), Research Grade
• Chinese Full Name: BioSIM 抗人 CD22 抗体（NCI-m971 生物类似药，科研用途）
• Supplier: InvivoCrown
• Catalog Number: SIM0094-1mg
• Specification: 1mg/vial
• Product Type: Secondary Antibody

Production Process and Background

This antibody is a recombinant biosimilar targeting human CD22, produced using protein-free in vitro cell culture technology. The entire process is completed in animal component-free production facilities, effectively avoiding the risk of contamination from exogenous animal-derived proteins.

The production process includes multi-step purification procedures, with key steps utilizing Protein A or G affinity chromatography technology to ensure the stability of antibody purity and biological activity, meeting the quality requirements for research-grade products.

Research Fields and Application Scenarios

Core Research Directions

Acute Lymphoblastic Leukemia (ALL): As a specific glycoprotein on the surface of B lymphocytes, CD22 is highly expressed in B-lineage acute lymphoblastic leukemia cells, making it an important research target in this field.

Applicable Application Types

• ELISA: Can be used for quantitative detection of human CD22 protein expression levels in samples;
• FACS (Flow Cytometry): Suitable for analyzing the proportion and phenotypic characteristics of CD22-positive cells in human cell populations;
• Functional Assay: Can be used to study CD22-related cell signaling pathways or functional activities;
• Research in vivo: Supports relevant basic research in animal models (following research ethics guidelines).

Immunological Properties

• Host Source: Humanized;
• Reactivity: Specific to human (Human) CD22 antigen only;
• Immunogen: For specific information, please refer to the product instruction manual.

Storage and Transportation Recommendations

Note: To maintain antibody activity, repeated freeze-thaw cycles should be avoided.

• Short-term Storage (1-2 weeks): Store at 4°C protected from light;
• Medium-term Storage (up to 12 months): Store at -20°C protected from light (aliquoting into small volumes is recommended to reduce freeze-thaw cycles);
• Long-term Storage: Store at -80°C protected from light (activity can be maintained long-term after aliquoting).

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult InvivoCrown.