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WKY大鼠在实验中作为SHR高血压大鼠的对照。
专业名称:WKY/NHnsja 毛色:白化
特性:
①忧郁、焦虑等行为异常;
②内分泌异常,容易应激(与Wistar大鼠相比,对应激刺激具有高反应性,可能与下丘脑-垂体-肾上腺轴和下丘脑-垂体-甲状腺轴异常调节有关);
③代谢异常。
研究应用领域:
用作高血压对照、多动症(ADHD)模型对照、抑郁症模,药物成瘾性研究,用于应激性溃疡或胃肠功能紊乱等方面的造模。
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