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牛磺熊去氧胆酸

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  • ¥416
  • YOYOBIO
  • 上海
  • YJ-B20921-20mg
  • 2025年11月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      2-8℃

    • 保质期

      见包装

    • 英文名

      Tauroursodeoxycholic acid

    • 库存

      大量现货

    • 供应商

      上海研谨生物

    • CAS号

      14605-22-2

    • 规格

      20mg

    牛磺熊去氧胆酸

    分析标准品,HPLC≥98%

    Tauroursodeoxycholic acid

    CAS号:14605-22-2

    分子式:C26H45NO6S

    分子量:499.7

    MDLMFCD00069496

    别名:牛磺熊去氧胆酸; 牛磺熊脱氧胆酸; 牛磺雄去氧胆酸

    货号

    规格/参数/品牌

    价格

    货期

    YJ-B20921-20mg

    分析标准品,HPLC≥98%

    416.00

    现货

    YJ-B20921-50mg

    分析标准品,HPLC≥98%

    650.00

    现货

    JS25092-1g

    98%

    255.00

    现货

    JS25092-5g

    98%

    485.00

    现货

    JS25092-25g

    98%

    1540.00

    现货

    JS25092-100g

    98%

    3580.00

    现货

     

    产品介绍

    熔点:173-175℃

    沸点:496.4℃ at 760mmHg

    比旋光度:(C=1, EtOH)+46

    外观:粉末

    溶解性:DMSO、乙醇等有机溶剂

    储存条件:2-8℃

    注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

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    图标文献和实验
    该产品被引用文献

    参考文献(39)

    39. [IF=5.9] Xiaojie Yang et al."Nuciferine alleviates cognitive impairment by modulating endoplasmic reticulum stress in D-galactose-induced aging mice."Food Bioscience.2025 Sep;71:107260

    38. [IF=3.1] Dan Yang et al."The defense role of luteolin-β-CD-MOF against acetaminophen induced liver toxicity by regulating of bile acids metabolism and gut microbiota."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2025 Nov;265:117033

    37. [IF=3.7] Xian rui Wang et al."Comprehensive Analysis of Bile Medicines Based on UHPLC-QTOF-MSE and Machine Learning."ACS Omega.2024;9(42):43264–43271

    36. [IF=2.3] Junyang Zhang et al."Loureirin B Ameliorates Glycolipid Metabolism Disorders in Ob/ob Mice by Regulating Bile Acid Levels and Modulating Gut Microbiota Composition."CHEMISTRY & BIODIVERSITY.2024 Nov;:e202401793

    35. [IF=3.1] Shen Wei et al."Tauroursodeoxycholic acid mitigates depression-like behavior and hippocampal neuronal damage in a corticosterone model of female mice."NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY.2024 Nov;:1-12

    34. [IF=2.1] Xiaodi Xu et al."Taurochenodeoxycholic Acid Improves Growth, Physiology, Intestinal Microbiota, and Muscle Development in Red Swamp Crayfish (Procambarus clarkii)."Fishes.2025 Feb;10(2):38

    33. [IF=2.7] Yuan Liu et al."Tauroursodeoxycholic acid inhibits endothelial-mesenchymal transition in high glucose-treated human umbilical vein endothelial cells."TISSUE & CELL.2025 Apr;93:102764

    32. [IF=5.3] Tong Tian-Tian et al."Pharmacological effects of bile acids on polycystic ovary syndrome via the regulation of chemerin."Chinese Medicine.2025 Dec;20(1):1-19

    31. [IF=4.4] Haoxiang Sun et al."Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway."Frontiers in Pharmacology.2025 Apr;16:

    30. [IF=6.1] Huanhuan Xue et al."Phillygenin ameliorates tight junction proteins reduction, fibrosis, and apoptosis in mice with chronic colitis via TGR5-mediated PERK-eIF2α-Ca2+ pathway."Journal of Pharmaceutical Analysis.2024 Jul;:101042

    29. [IF=5.4] Yingkun Sheng et al."Dan-shen Yin promotes bile acid metabolism and excretion to prevent atherosclerosis via activating FXR/BSEP signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118209

    28. [IF=13.6] Anfei Liu et al."Bile acid metabolism is altered in learning and memory impairment induced by chronic lead exposure."JOURNAL OF HAZARDOUS MATERIALS".2024 Jun;471:134360

    27. [IF=5.6] Dan Yang et al."Luteolin-β-CD-MOF prevents against acetaminophen-mediated liver damage by controlling ferroptosis through GSH/GPX4/SLC7A11 signal axis."Journal of Functional Foods".2024 May;116:106138

    26. [IF=6.1] Shurui Zhang et al."Lactiplantibacillus plantarum ATCC8014 Alleviates Postmenopausal Hypercholesterolemia in Mice by Remodeling Intestinal Microbiota to Increase Secondary Bile Acid Excretion."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY".2024;72(12):6236–6

    25. [IF=5.8] Junke Zhao et al."Tauroursodeoxycholic acid liposome alleviates DSS-induced ulcerative colitis through restoring intestinal barrier and gut microbiota."COLLOIDS AND SURFACES B-BIOINTERFACES".2024 Apr;236:113798

    24. [IF=7.9] Jing Yang et al."Protopine ameliorates OVA-induced asthma through modulatingTLR4/MyD88/NF-κB pathway and NLRP3 inflammasome-mediated pyroptosis."PHYTOMEDICINE".2024 Feb;:155410

    23. [IF=5.6] Shengyun Dai et al."Synergistic effect of Euphorbia kansui stir-fried with vinegar and bile acids on malignant ascites effusion through modulation of gut microbiota."Frontiers in Pharmacology.2023; 14: 1249910

    22. [IF=4.7] Wu Nian et al."Rapid Simultaneous Determination of Four Ganoderic Acids in Ganoderma (Chinese Name: Lingzhi) by Direct Infusion–Multiple Reaction Monitoring Cubed."Journal of Analysis and Testing.2023 Nov;:1-11

    21. [IF=5.1] Weng Jiaxian et al."Tauroursodeoxycholic Acid Inhibited Apoptosis and Oxidative Stress in H2O2-Induced BMSC Death via Modulating the Nrf-2 Signaling Pathway: the Therapeutic Implications in a Rat Model of Spinal Cord Injury."MOLECULAR NEUROBIOLOGY.2023 Nov

    20. [IF=3.9] Ya-nan Ou-Yang et al."High-salt diet induces dyslipidemia through the SREBP2/PCSK9 pathway in dahl salt-sensitive rats."BIOCHIMIE.2023 Oct;:

    19. [IF=4.212] Yingkun Sheng et al."PARP-1 inhibitor alleviates liver lipid accumulation of atherosclerosis via modulating bile acid metabolism and gut microbes."Molecular Omics.2023 May;:

    18. [IF=6.388] Meng-ying Chen et al."Psoralen induces liver injury and affects hepatic bile acids metabolism in female and male C57BL/6J mice."PHYTOTHERAPY RESEARCH.2023 Feb;:

    17. [IF=4.571] Yuanjie Wen et al."The role of the farnesoid X receptor in quadruple anti-tuberculosis drug-induced liver injury."TOXICOLOGY.2022 Jun;476:153256

    16. [IF=3.318] Hongda Sheng et al."Identification of bioactive ingredients from Babaodan using UPLC-QTOF-MS analysis combined with network pharmacology guided bioassays."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Aug;120

    15. [IF=5.988] Weiwei Li et al."Integrated Lipidomics and Metabolomics Study of Four Chemically Induced Mouse Models of Acute Intrahepatic Cholestasis."Frontiers in Pharmacology.2022; 13: 907271

    14. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885

    13. [IF=5.396] Juan Wu et al."Sargassum fusiforme polysaccharide is a potential auxiliary substance for metformin in the management of diabetes."Food Funct. 2022 Feb;:

    12. [IF=0.252] Yi Dong et al."Mechanism of tauroursodeoxycholic acid-mediated neuronal protection after acute spinal cord injury through AKT signaling pathway in rats."Int J Clin Exp Patho. 2020; 13(9): 2218–2227

    11. [IF=3.935] Song Lin et al."A systemic combined nontargeted and targeted LC-MS based metabolomic strategy of plasma and liver on pathology exploration of alpha-naphthylisothiocyanate induced cholestatic liver injury in mice."J Pharmaceut Biomed. 2019 Jul;171:180

    10. [IF=5.396] Cong Liang et al."Lactiplantibacillus plantarum H-87 prevents high-fat diet-induced obesity by regulating bile acid metabolism in C57BL/6J mice."Food Funct. 2021 May;12(10):4315-4324

    9. [IF=5.396] Shiming Huang et al."A sulfated polysaccharide from Gracilaria Lemaneiformis regulates cholesterol and bile acid metabolism in high-fat diet mice."Food Funct. 2019 Jun;10(6):3224-3236

    8. [IF=5.878] Min Wen et al."Geniposide suppresses liver injury in a mouse model of DDC-induced sclerosing cholangitis."Phytother Res. 2021 Jul;35(7):3799-3811

    7. [IF=6.558] Qingqing Song et al."Binary code, a flexible tool for diagnostic metabolite sequencing of medicinal plants."Anal Chim Acta. 2019 Dec;1088:89

    6. [IF=8.322] Hou  Yonghui et al."Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response."J Neuroinflamm. 2021 Dec;18(1):1-13

    5. [IF=3.361] Qingqing Song et al."Polarity-extended quantitative analysis of bear bile and its analogues using serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring."Rsc Adv. 2017 Nov;7(83):52822-52831

    4.  Song Lin, Tian-yang Wang, Hua-rong Xu, Xin-nong Zhang, Qi Wang, Ran Liu, Qing Li, Kai-shun Bi,

    A systemic combined nontargeted and targeted LC-MS based metabolomic strategy of plasma and liver on pathology exploration of alpha-naphthylisothiocyanate induce

    3.  Wang, Tianyang, et al. "Metabolomic profile perturbations of serum, lung, bronchoalveolar lavage fluid, spleen and feces in LPS-induced acute lung injury rats based on HPLC-ESI-QTOF-MS." Analytical and bioanalytical chemistry 412.5 (2020): 1215-1234.

    2.  曹妍,李婷,常安琪,蒋珍珍,于娟,屠鹏飞,宋月林.蛇胆中胆汁酸类化学成分分析[J].中国中药杂志,2021,46(01):130-138.

    1.  杨金伟,赵灿,刘秀,吴勇军,喻嵘.左归降糖舒心方含药血浆对ox-LDL诱导小鼠巨噬细胞泡沫化和凋亡的影响[J].南京中医药大学学报,2020,36(03):370-375.

    相关实验
    • 冰桶挑战已多年,研究进展怎样?Nature,NEJM 报道神经退行性疾病出路竟在免疫

      -Taurursodiol for Amyotrophic Lateral Sclerosis 研究成果, 公布了 CENTAUR 2 期临床试验结果。这项结果表明,AMX0035 疗法可显著延缓 ALS 患者的疾病进展。AMX0035 是一种联合疗法,苯丁酸(Phenylbutyrate,PB)和牛磺熊去氧胆酸(Tauroursodeoxycholic Acid,TUDCA)的固定组合,通过阻滞源于线粒体和内质网(ER)的关键细胞死亡通路来减少神经元死亡和炎症。

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    牛磺熊去氧胆酸
    ¥416