ab18638-100ug，Anti-HSV1 gD ant

The HSV1 gD protein also known as glycoprotein D plays a mechanical role in herpes simplex virus 1 (HSV-1) entry. It binds to cellular receptors initiating viral fusion with host cells. Glycoprotein D (gD) has a molecular mass of about 39-41 kDa and is expressed on the surface of the viral envelope. The interaction with host cell receptors such as nectin-1 is essential for the virus to penetrate the cell membrane and establish infection within epithelial and neuronal tissues. This process causes HSV-1 to localize in areas where it can reactivate later./ Biological function summary/ Glycoprotein D facilitates virus entry into the host by interacting with entry mediators. Although gD itself is not part of a larger protein complex its interaction with host cell receptors is essential to trigger downstream events necessary for viral replication. The binding of gD to cellular receptors initiates conformational changes that lead to the fusion of the viral envelope with the cell membrane. This fusion is a critical step in the viral life cycle allowing the viral capsid to enter the host cell cytoplasm and ultimately reach the nucleus for replication./