ab18633-100ug，Anti-HIV1 gp41 a

The HIV1 gp41 protein also known as the gp41 HIV protein is a glycoprotein that plays a mechanical role in the virus's capacity to fuse with host cells. This protein is 41 kDa in mass and is part of the viral envelope expressed on the surface of the HIV virus. Gp41 works closely with the gp120 protein to facilitate the fusion process a critical step in viral entry into lymphocytes. The 1d4 is sometimes used to refer to certain related domains or epitopes within the gp41 structure./ Biological function summary/ During the infection process gp41 acts by mediating membrane fusion between the HIV viral envelope and the host cell membrane. It forms part of the Env complex consisting of gp120 and gp41 proteins which together create the functional envelope glycoprotein spike on the virus. This spike binds to receptors on the host cell such as the CD4 molecule which initiates changes that reveal the gp41 protein allowing it to insert into the host cell membrane and pull the viral and cellular membranes together.