ab18530-100ug，Anti-TBX1 antibo

TBX1 also known as T-box protein 1 is a transcription factor with a molecular weight of around 58 kDa. It belongs to the T-box gene family and plays a role in regulating transcriptional activity of specific genes. TBX1 expresses mostly in mesodermal and neural crest cell derivatives during embryonic development. High expression levels occur in the pharyngeal arches which are structures important for the development of facial and neck regions./ Biological function summary/ This protein influences developmental processes involving tissues derived from the pharyngeal arches. TBX1 functions as a part of a regulatory network important for proper embryogenesis. It does not form part of a stable complex but interacts with many cofactors to direct the transcription of genes responsible for cell proliferation differentiation and migration. The correct functioning of TBX1 ensures normal formation and patterning of the craniofacial structures cardiac outflow tract and great vessels./ Pathways/ TBX1 engages in the retinoic acid signaling pathway which is essential for the regulation of gene expression during development. It also plays an important role in the fibroblast growth factor (FGF) signaling pathway. These pathways involve related proteins like FGF8 and FGF10 which are important for coordinated signaling during morphogenesis. TBX1's regulatory influence on these pathways highlights its importance in developmental signaling networks./