ab19878-100ug，Anti-STELLAR ant

STELLAR also known as 'STELLA' or 'DPPA2' acts mechanically as a regulator of pluripotency and early embryonic development. It weighs approximately 17 kDa. This protein expresses itself in pluripotent stem cells and germ cells. Researchers have found subcellular localization of STELLAR mainly in the nucleus suggesting critical functions in gene regulation during cell differentiation./ Biological function summary/ The protein plays an important role in maintaining cell totipotency and germ cell specification. STELLAR interacts with several cellular complexes that are pivotal during embryogenesis. By regulating specific genes STELLAR contributes to the repression of inappropriate gene expression in pluripotent cells impacting cellular fate outcomes during development./ Pathways/ STELLAR participates in the pluripotency regulatory network involving significant pathways like the Wnt signaling pathway. This protein's regulatory mechanisms align with other transcription factors such as NANOG and OCT4 highlighting its role in the maintenance of the pluripotent state. The interplay among these factors establishes a complex circuit essential for the retention of stem cell properties./