ab17018-100ug，Anti-FBXL2 antib

FBXL2 also known as F-box and leucine-rich repeat protein 2 is involved in protein degradation mechanisms. It is part of a SCF (SKP1-Cullin-F-box) complex and functions as a ubiquitin ligase. FBXL2 targets proteins for ubiquitination tagging them for proteasomal degradation. Weighing approximately 49 kDa FBXL2 shows expression in various tissues including the liver heart and brain. Its role in maintaining protein homeostasis highlights its importance in cellular processes./ Biological function summary/ The FBXL2 protein maintains cellular protein quality by regulating the turnover of specific substrates. It forms a complex with SKP1 and Cullin-2 in the ubiquitin-proteasome pathway. FBXL2 mediates the degradation of important regulatory proteins influencing the cell cycle and signal transduction. This activity impacts cellular responses to stress and environmental changes ensuring proper cellular adaptation./