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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-CD1c antibody [M241]
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
50ug
CD1c also known as CD1c molecule or R7 is a transmembrane glycoprotein with a molecular weight of approximately 43 kDa. It belongs to the CD1 family of glycoproteins which share structural similarity to major histocompatibility complex (MHC) proteins. CD1c presents lipid and glycolipid antigens to T cells. It is expressed on professional antigen-presenting cells (APCs) like dendritic cells B cells and some monocytes. This expression allows CD1c to function in the immune response by presenting specialized antigens to T cells./
Biological function summary/
The function of CD1c involves the presentation of lipid antigens which plays a role in immune recognition. CD1c is a part of a complex that includes β2-microglobulin which stabilizes its structure for antigen presentation. CD1c contributes to the immune surveillance by enabling the recognition of microbial lipid antigens as well as self-lipids by specific T cell subsets. This function supports the body's immune defense by identifying and reacting to potential pathogenic lipids./
Pathways/
CD1c is involved in immune response pathways that center around antigen presentation. It interacts with other proteins like CD1a CD1b and CD1d expanding the range of antigens that T cells can recognize. CD1c participates in the lipid antigen presentation pathway influencing both innate and adaptive immunity. The presentation of lipid antigens by CD1c to T cells can trigger signaling pathways that affect both immune activation and resolution./
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文献和实验该产品被引用文献
Cellular and molecular gastroenterology and hepatology 5:31-49 | PubMed 29188232
2017
Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System.
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Applications
Unspecified application
Species
Unspecified reactive species
Emilie Duchalais, Christophe Guilluy, Steven Nedellec, Melissa Touvron, Anne Bessard, Yann Touchefeu, Céline Bossard, Hélène Boudin, Guy Louarn, Michel Neunlist, Laurianne Van Landeghem
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ab18216-50ug,Anti-CD1c antibody [M241]
¥3265


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