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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-MRP4 antibody [M4I-10]
- 应用范围:
仅用科研
- 保质期:
见瓶身
- 库存:
99
- 供应商:
嘉兴亦高
- 保存条件:
-20°
- 规格:
500ul
he MRP4 protein also known as Multidrug Resistance Protein 4 or ABCC4 is an ATP-binding cassette transporter with a mass of approximately 150 kDa. This protein is expressed in various tissues including the liver kidney and brain. It plays a mechanical role by transporting organic anions drugs and other xenobiotic compounds across cellular membranes. MRP4 is part of the wider ATP-binding cassette (ABC) transporter family which actively pumps substrates against concentration gradients using ATP hydrolysis./
Biological function summary/
MRP4 impacts processes like pharmacokinetics and drug metabolism. The protein contributes to the efflux of endogenous substrates and medication from cells affecting their absorption and excretion. MRP4 also functions as part of a larger transporter complex working with other similar proteins to manage cellular detoxification systems. The MRP4 transporter maintains cellular homeostasis by removing harmful substances supporting cellular defense mechanisms against xenobiotic and endogenous compounds./
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文献和实验该产品被引用文献
Molecular biology reports 49:11881-11890 | PubMed 36224445
2022
Decreased ZO1 expression causes loss of time-dependent tight junction function in the liver of ob/ob mice.
out
Applications
Unspecified application
Species
Unspecified reactive species
Yuya Tsurudome, Nao Morita, Michiko Horiguchi, Kentaro Ushijima
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ab15602-500ul,Anti-MRP4 antibody [M4I-10]
¥3307


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