ab15085-100ug，Anti-Polyoma vir

The Polyoma virus Medium T antigen also called Middle T antigen belongs to the early proteins expressed by Polyomaviruses. Medium T antigen has a molecular mass of about 57 kilodaltons (kDa). This protein is located in the cytoplasm and is anchored to the cellular membrane. Its expression occurs predominantly during the early phase of viral infection. The Medium T antigen has an important role in transforming host cells primarily through its interactions with cellular signaling components./ Biological function summary/ The Middle T antigen facilitates oncogenic transformation by associating with host cell proteins that regulate various signaling pathways. This protein engages in forming a complex with cellular kinases such as Src family kinases. By acting as a scaffold protein it effectively recruits and activates these kinases which contributes to unregulated cell growth. Through these interactions Medium T antigen alters normal cell signaling dynamics and promotes cellular transformation an important step in viral proliferation./