ab14628-50ug，Anti-PDE4 antibod

PDE4 or phosphodiesterase 4 is an enzyme that specifically hydrolyzes cyclic adenosine monophosphate (cAMP) into AMP which regulates intracellular levels of cAMP. PDE4 subfamily includes four isoforms: PDE4A PDE4B PDE4C and PDE4D each with unique expression patterns and roles. The approximate molecular weight of PDE4 enzymes varies depending on isoform but typically around 80-100 kDa. This enzyme is widely distributed in the body with expression found primarily in the brain heart lungs and immune cells where it modulates cellular responses to hormonal signals./ Biological function summary/ PDE4 plays an important role in modulating inflammatory responses and immune cell activation due to its control over cAMP levels. By degrading cAMP PDE4 impacts the signaling pathways that govern inflammation and immune responses. This enzyme is often found in complex with other proteins that help localize and regulate its activity within cells. It plays a significant role in neuron communication and neuroplasticity affecting learning and memory processes./