ab13810-100ug，Anti-TRIF antibo

TRIF also known as TIR-domain-containing adapter-inducing interferon-β is an adapter protein that plays an important role in the immune response. It has a molecular mass of about 85 kDa. TRIF is expressed in various tissues but most highly in immune cells like macrophages and dendritic cells. Mechanically TRIF acts within the signaling pathways by connecting Toll-like receptors (TLR) with downstream signaling molecules. It is essential for activating pathways that lead to the production of type I interferons and other cytokines./ Biological function summary/ TRIF is part of the innate immune response mechanism. It functions as a central component in signal transduction processes especially in response to pathogen-associated molecular patterns (PAMPs). TRIF often forms complexes with other signaling proteins to activate transcription factors such as IRF3 and NF-kB which stimulate the expression of inflammatory cytokines and antiviral genes. This function allows the body to respond quickly to infections and initiate immune defenses./