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ab13518-100ul,Anti-TPN antibod

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  • ¥3231
  • Abcam
  • ab13518-100ul
  • 2025年11月01日
  • 仅用科研
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Anti-TPN antibody

    • 应用范围

      仅用科研

    • 保质期

      见瓶身

    • 库存

      99

    • 供应商

      嘉兴亦高

    • 保存条件

      -20°

    • 规格

      100ul

    TPN also known as Thyroid Peroxidase is an enzyme critical for thyroid hormone synthesis. The protein has a molecular weight of approximately 105 kDa. It is mainly expressed in the thyroid gland where it facilitates iodine organification a critical step in the production of thyroid hormones. TPN is a membrane-bound glycoprotein localized in the apical membrane of thyrocytes allowing it to participate directly in hormone production./ Biological function summary/ The enzyme TPN operates at the interface of thyroglobulin and iodide catalyzing the iodination of tyrosine residues within thyroglobulin. This process facilitated by TPN is key to the synthesis of thyroxine (T4) and triiodothyronine (T3) the main thyroid hormones. TPN functions within a larger complex involving hydrogen peroxide and cofactor flavin adenine dinucleotide (FAD) which together drive efficient hormone biosynthesis. Therefore any disruption in TPN activity can affect the availability of thyroid hormones./

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    图标文献和实验
    该产品被引用文献
    Frontiers in immunology 13:992060 | PubMed 36311733 2022 An antigen processing and presentation signature for prognostic evaluation and immunotherapy selection in advanced gastric cancer. out Applications Unspecified application Species Unspecified reactive species Ke-Wei Wang, Mei-Dan Wang, Zi-Xi Li, Ben-Shun Hu, Jun-Jie Wu, Zheng-Dong Yuan, Xiao-Long Wu, Qin-Fang Yuan, Feng-Lai Yuan
    相关实验
    • Protocol for anti-HA antibody Western Blotting

      film for ~2 mins. Notes on the primary antibody: Source : Covance/Babco Description: Crude ascites fluid monoclonal anti-HA antibody (CATLN#135032002, 11mms-101R, 0.5 ml) Handling: Aliquoted into 10ul portions in -20℃ Internal notes: labelled anti

    • Antibody Purification

      Blue Regeneration Buffer 2 M guanidine HCl or 1.5 M Na thiocyanate HiTrap Storage Buffer 10 mM Tris 7.5 1 ml 1M Tris 7.5 0.1 mM EDTA 20 ul 500 mM EDTA 50 mM NaCl 1 ml 5M NaCl 0.1% azide 0.1 g Na azide up to 100

    • Antibody Staining of Dissected Gonads

      at least 4 hr at RT or overnight at 4 oC (Overnight at 4 oC is probably best).   *Wash in PBTw,  3-4 x 5 min *Wash in PBS containing 100 ng/ml DAPI. *Wash in PBTw, once *Place in 80% glycerol containing anti-fade reagent (e.g., Dapco) about 20 ­ 30 ul

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    ab13518-100ul,Anti-TPN antibody
    ¥3231