- ￥99 - 999
- Sigma
- 进口
- Z0127-10MG
- 2025年10月30日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温
- 库存：
现货
- 供应商：
联硕生物
- CAS号：
91940-87-3
- 规格：
1瓶
应用
Zatebradine hydrochloride has been used:
as an If blocker to study its effects on cardiomyocyte clusters (CMCs) [1]
as a hyperpolarization-activated and cyclic nucleotide-gated (HCN) channel inhibitor to study its effects on viability of degenerating rod or cone photoreceptors in mice [2]
as a bradycardiac agent to study its effects on tachycardia and elevated temperature in fish [3]
生化/生理作用
HCN channel blocker: blocker of neuronal Ih, related cardiac If channels and ATP-sensitive Kir channels.
Zatebradine is a bradycardiac agent.
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文献和实验CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 and p42/44MAPK dependent mechanisms
Fang W B, et al.
The Journal of biological chemistry, jbc-M112 (2012)
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