C22orf29 Rabbit pAb(bs-15135R)-50ul/100ul/200ul

C22orf29 Rabbit pAb(bs-15135R)

-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-15135R
  • 2025年10月25日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-15135R
    英文名称C22orf29 Rabbit pAb
    中文名称22号染色体开放阅读框29抗体
    英文别名C22orf29; CV029_HUMAN; Uncharacterized protein C22orf29.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human C22orf29
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量39 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK.
    亚细胞定位Mitochondrion.
    组织特异性Ubiquitously expressed.
    功能Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    C22orf29 Rabbit pAb(bs-15135R)
    Sample:293T Cell (Human)Lysate at 40 ug
    Primary: Anti-FBXL3(bs-15135R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
    Predicted band size: 39kD
    Observed band size: 45kD

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