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SLC32A 1 Rabbit pAb(bs-10958R)

-50ul/100ul/200ul
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  • ￥1180 - 2800
  • Bioss已认证
  • bs-10958R
  • 2025年10月25日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-10958R
    英文名称SLC32A 1 Rabbit pAb
    中文名称氨基丁酸转运蛋白VGAT抗体
    英文别名VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32(GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Pig, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLC32A1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量57 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cytoplasmic vesicle membrane; Multi-pass membrane protein
    组织特异性Retina. Expressed throughout the horizontal cells or more specifically at the terminals.
    相似性Belongs to the amino acid/polyamine transporter 2 family.
    功能Involved in the uptake of GABA and glycine into the synaptic vesicles.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {WB}{1:500-2000}

     

    产品细节图片1
    25 ug total protein per lane of various lysates (see on figure) probed with SLC32A 1 polyclonal antibody, unconjugated (bs-10958R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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    该产品被引用文献

    [IF={{ 3.9 }}] {Wang Meng. et al. The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo. SCI REP-UK. 2025 May;15(1):1-14} {WB} {Rat}

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    文献支持
    SLC32A 1 Rabbit pAb(bs-10958R)-50ul/100ul/200ul
    ￥1180 - 2800