Sample:
Lane 1: Mouse Kidney tissue lysates
Lane 2: Mouse Colon tissue lysates
Lane 3: Mouse Spleen tissue lysates
Lane 4: Rat Kidney tissue lysates
Lane 5: Rat Liver tissue lysates
Lane 6: Rat Spleen tissue lysates
Lane 7: Human Jurkat cell lysates
Lane 8: Human THP-1 cell lysates
Lane 9: Human A431 cell lysates
Lane 10: Human HepG2 cell lysates
Lane 11: Human MCF-7 cell lysates
Lane 12: Human U87MG cell lysates
Primary: Anti- TGF alpha (bs-0066R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kDa
Observed band size: 15 kDa
- ￥1180 - 1980
- Bioss
- bs-0066R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 产品编号 | bs-0066R |
| 英文名称 | TGF alpha Rabbit pAb |
| 中文名称 | 转移生长因子α抗体 |
| 英文别名 | EGF like TGF; ETGF; TFGA; TGF A; TGF type 1; TGFA; Transforming growth factor alpha; Transforming growth factor alpha precursor; Wa1; Waved 1; TGFA_HUMAN; TGFα; TGF-α; TGF α. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse TGF-alpha |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 17 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Growth factors > TGF Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors Cardiovascular > Angiogenesis > Growth Factors > TGF Signal Transduction > Growth Factors/Hormones > TGF |
| 亚基 | Interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP, is required for the targeting to the cell surface. In the endoplasmic reticulum, in its immature form (i.e. with a prosegment and lacking full N-glycosylation), interacts with CNIH. In the Golgi apparatus, may form a complex with CNIH and GORASP2. Interacts (via cytoplasmic C-terminal domain) with NKD2. |
| 亚细胞定位 | Transforming growth factor alpha: Secreted, extracellular space. Protransforming growth factor alpha: Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. |
| 相似性 | Contains 1 EGF-like domain. |
| 功能 | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar (By similarity). Inhibitor of acid secretion. Inhibitor of aminopyrine uptake in parietal cells (in vitro). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 5.17 }}] {Sun et al. The correlation between microRNA490-3p and TGFα in endometrial carcinoma tumorigenesis and progression. (2016) Oncotarge. 7:9236-49} {WB} {Human}
相关实验
Protocol for intracytoplasmic staining of cytokines for FACS analysis
; Pharmingen 18195A) for FL2 anti-IL10 (JES5.16E3-PE; Pharmingen 18435A) for FL1 anti-TGF-beta (rabbit anti pan TGF-beta; R&D Systems AB-100-NA home made FITC conjugate) for FL2 8) Wash extensively in saponin buffer followed by PBS + 0.1% azide
T 2000/3000 进口分装 F2036 兔基质金属蛋白酶-3(rabbit MMP-3) ELISA 48T/96T 2000/3000 进口分装 F2037 兔血小板活化因子 (rabbit PAF) ELISA 48T/96T 2000/3000 进口分装 F2038 兔S100 b ELISA 48T/96T 2000/3000 进口分装 F2039 兔转化生长因子-β1 (rabbit TGF- b 1) ELISA 48
T 2000/3000 进口分装 F2036 兔基质金属蛋白酶-3(rabbit MMP-3) ELISA 48T/96T 2000/3000 进口分装 F2037 兔血小板活化因子 (rabbit PAF) ELISA 48T/96T 2000/3000 进口分装 F2038 兔S100 b ELISA 48T/96T 2000/3000 进口分装 F2039 兔转化生长因子-β1 (rabbit TGF- b 1) ELISA 48
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TGF alpha Rabbit pAb(bs-0066R)-50ul/100ul
￥1180 - 1980
