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- C1997-25MG
- 2026年04月30日
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- 库存：
999
- 供应商：
鹿森生物
- 规格：
25MG
Biochem/physiol Actions
CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent. This is a different site from those involved in the activities of other agonists such as FTY720 and SEW2871.
CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo.
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文献和实验在0.015 625～0.25mg/mL范围内与所测得的相应峰面积呈良好的线性关系。 2.5 精密度实验精密吸取0.0625mg/ml的对照品溶液10μl进样，重复进样6次，按上述色谱条件测定桔梗皂苷D的峰面积分别为22 561，22 108，22 235，22 463，22 412，22 369。RSD＝0.73％。结果表明本方法的精密度良好。 2.6 稳定性实验精密吸取供试品溶液，按上述色谱条件，每隔2 h进样1次，共进样6次，桔梗皂苷D的峰面积分别为30 938，32
-EUR Collaborative Group. Systolic Hypertension in comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet,1997,350:757-764. 8. Agabiti Rosei E, Dal Palu C, Leonetti G, et al for the VHAS investigators
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