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- 详细信息
- 技术资料
- 保存条件:
RT
- 保质期:
见标签
- 库存:
999
- 供应商:
联硕生物
- CAS号:
3056-17-5
- 规格:
10MG
Application
2′,3′-Didehydro-3′-deoxythymidine has been used in cell treatment.[1] It has also been used as a drug in Caenorhabditis elegans to study drug induced mitochondrial toxicity.[2] It has also been used in the preclinical evaluation of GS-9160.[3]
Biochem/physiol Actions
2′,3′-Didehydro-3′-deoxythymidine is a nucleoside analog, which inhibits HIV replication in vitro. Stavudine has the ability to enter the cells by non-facilitated diffusion. It possesses inhibitory activity against moloney murine leukemia virus, friend murine leukemia virus and simian immunodeficiency virus.[4]
General description
2′,3′-Didehydro-3′-deoxythymidine (d4T), a pyrimidine analogue is the inhibitor of reverse transcriptase.
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