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- Sigma
- 进口
- C8753-10MG
- 2026年04月29日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
RT
- 保质期：
见标签
- 库存：
999
- 供应商：
联硕生物
- 规格：
10MG
Application
Cholesteryl arachidoante was oxidized and used to study the biological effects.[1][2]
Biochem/physiol Actions
Cholesteryl arachidonate is a cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.[3] The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans.[4]
Preparation Note
Cholesteryl arachidonate is a clear, colorless viscous liquid in chloroform.
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文献和实验7 Detecting Cholesteryl Ester Transfer Protein in Plasma
Transport of triglycerides (TGs) and cholesteryl esters (CEs) in plasma can be viewed as taking place via two major groups of lipoproteins, the TG-rich lipoproteins (chylomicrons and VLDL), on one hand, and the cholesterol-rich lipoproteins
Hormone-Sensitive Lipase and Neutral Cholesteryl Ester Lipase
, but is also expressed in steroidogenic and muscle tissues (3 ,4 ). It has been proposed that the function of HSL in steroidogenic tissues is to hydrolyze stored cholesteryl esters, in order to provide free cholesterol for the synthesis of steroid hormones
of the above techniques for lipidomic analysis of the autoxidation products of cholesteryl esters and glycerolipids as practiced in the authors’ laboratories.
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