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- Elabscience
- 湖北武汉
- E-AB-13198
- 2025年10月23日
- IHC;ELISA
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Rabbit
- 应用范围：
IHC;ELISA
- 抗体英文名：
DIO2 Polyclonal Antibody
- 抗体名：
DIO2 Polyclonal Antibody_货号:E-AB-13198_多克隆抗体
- 规格：
200μL/120μL/60μL/20μL
| 规格： | 200μL | 产品价格： | ￥2365.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥1640.0 |
| 规格： | 60μL | 产品价格： | ￥1010.0 |
| 规格： | 20μL | 产品价格： | ￥420.0 |
DIO2 Polyclonal Antibody
| Verified Samples |
Verified Samples in IHC: Human cervical cancer
|
| Dilution |
IHC 1:25-1:100
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Synthetic peptide of human DIO2
|
| Abbre |
DIO2
|
| Synonyms |
5DII, D2, DIO2, DIOII, Deiodinase, EC 1.97.1.10, IOD2, ITDI2, SelY, TXDI2, Thyroxine deiodinase, Type 2 DI, Type 2 iodothyronine deiodinase, Type II 5' deiodinase, Type II iodothyronine deiodinase, Type-II 5''-deiodinase, iodothyronine, type II
|
| Swissprot |
Q92813
|
| Cellular Localization |
Membrane.
|
| Concentration |
0.9 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% sodium azide and 50% glycerol, pH 7.4.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer, Metabolism, Neuroscience, Signal Transduction
|
| Conjugation |
Unconjugated
|
| Background |
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
|
DIO2 Polyclonal AntibodyElabscience®提供8000+经过实验验证的高品质一抗，主要包括： 流式抗体、 单抗、 多抗、 重组抗体、 内参/标签抗体、 乙酰化/磷酸化/甲基化抗体、 磁珠/凝胶偶连抗体、 病毒抗体等。
DIO2 Polyclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
DIO2 Polyclonal Antibody产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model
IF:4.848
Journal:Frontiers in Oncology
DOI:10.3389/fonc.2020.01771
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