- ￥772
- Sigma-Aldrich
- 进口
- 82280-250ML
- 2025年10月18日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温
- 保质期：
根据瓶身LOT号查询
- 英文名：
1,2-Propanediol
- 库存：
有现货
- 供应商：
浙江羽翔生物科技有限公司
- CAS号：
57-55-6
- 规格：
250ML
属性
产品名称
1,2-丙二醇, puriss. p.a., ACS reagent, ≥99.5% (GC)
等级
ACS reagent
puriss. p.a.
质量水平
200
蒸汽密度
2.62 (vs air)
蒸汽压
0.08 mmHg ( 20 °C)
方案
≥99.5% (GC)
表单
viscous liquid
自燃温度
779 °F
保质期
3 yr
expl. lim.
12.5 %
杂质
≤0.003% free acid (as CH3COOH)
≤0.1% water
蒸发残留物
≤0.005%
灼烧残渣
<0.005% (as SO4)
折射率
n20/D 1.432 (lit.)
n20/D 1.433
沸点
187 °C (lit.)
mp
−60 °C (lit.)
密度
1.036 g/mL at 25 °C (lit.)
痕量阴离子
chloride (Cl-): ≤1 mg/kg
sulfate (SO42-): ≤20 mg/kg
痕量阳离子
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤5 mg/kg
SMILES字符串
CC(O)CO
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
InChI key
DNIAPMSPPWPWGF-UHFFFAOYSA-N
一般描述
应用
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Looking at the metabolic consequences of the colchicine-based in vivo autophagic flux assay.
Monitoring autophagic flux in vivo or in organs remains limited and the ideal methods relative to the techniques possible with cell culture may not exist. Recently, a few papers have demonstrated the feasibility of measuring autophagic flux in vivo by intraperitoneal (IP) injection of pharmacological agents (chloroquine, leupeptin, vinblastine, and colchicine). However, the metabolic consequences of the administration of these drugs remain largely unknown. Here, we report that 0.8 mg/kg/day IP colchicine increased LC3-II protein levels in the liver of fasted trout, supporting the usefulness of this drug for studying autophagic flux in vivo in our model organism. This effect was accompanied by a decrease of plasma glucose concentration associated with a fall in the mRNA levels of gluconeogenesis-related genes. Concurrently, triglycerides and lipid droplets content in the liver increased. In contrast, transcript levels of β-oxidation-related gene Cpt1a dropped significantly. Together, these results match with the reported role of autophagy in the regulation of glucose homeostasis and intracellular lipid stores, and highlight the importance of considering these effects when using colchicine as an in vivo "autophagometer."
技术资料暂无技术资料 索取技术资料
