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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein corresponding to amino acids 1-261 of human hnRNP M (NP_112480) produced in E. coli
- 亚型:
IgG2b
- 形态:
Purified IgG - liquid
- 克隆性:
PrecisionAb Monoclonal
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
OTI3F3
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
IP, WB
- 浓度:
IgG concentration 0.5 mg/ml.
- 抗体名:
hnRNP M antibody | OTI3F3
- 规格:
100 µl
Mouse anti Human hnRNP M antibody recognizes heterogeneous nuclear ribonucleoprotein M (hnRNP M), also known as CEA receptor, N-acetylglucosamine receptor 1, heterogenous nuclear ribonucleoprotein M4 and hnRNA-binding protein M4.
Encoded by the HNRNPM gene, hnRNP M belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoprotein M has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants (provided by RefSeq, Aug 2011).
Mouse anti Human hnRNP M antibody detects a band of 77 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Encoded by the HNRNPM gene, hnRNP M belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoprotein M has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants (provided by RefSeq, Aug 2011).
Mouse anti Human hnRNP M antibody detects a band of 77 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
储存信息
This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoprecipitation | ✓ | ||
| Western Blotting | ✓ | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Mouse anti hnRNP M,clone OTI3F3
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