- 询价
- BIO-RAD
- MCA2653
- 2025年10月17日
- E, F
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human CD137-Fc.
- 亚型：
IgG2a
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
JG1.6A
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
E, F
- 浓度：
IgG concentration 1.0mg/ml
- 抗体名：
CD137 antibody | JG1.6A
- 规格：
0.2 mg
Rat anti Human CD137 antibody, clone JG1.6A recognizes human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and regulates T-cell activation and proliferation.
Rat anti Human CD137 antibody, clone JG1.6A induces γ-interferon activity in isolated T-cells as measured by ELISA (Rajendran et al. 2019).
Rat anti Human CD137 antibody, clone JG1.6A induces γ-interferon activity in isolated T-cells as measured by ELISA (Rajendran et al. 2019).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | ✓ | ||
| Flow Cytometry | ✓ |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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文献和实验该产品被引用文献
Further Reading
- Pollok, K.E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function.
J Immunol. 150 (3): 771-81. - Alderson, M.R. et al. (1994) Molecular and biological characterization of human 4-1BB and its ligand.
Eur J Immunol. 24 (9): 2219-27. - Schwarz, H. et al. (1997) CD137, a member of the tumor necrosis factor receptor family, is located on chromosome 1p36, in a cluster of related genes, and colocalizes with several malignancies.
Biochem Biophys Res Commun. 235 (3): 699-703. - Cannons, J.L. et al. (2001) 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy.
J Immunol. 167 (3): 1313-24.
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Rat anti Human CD137，clone JG1.6A
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