- 询价
- BIO-RAD
- MCA1340T
- 2025年10月17日
- E, R
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified human tumour necrosis factor receptor type 1.
- 亚型：
IgG2a
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
H398
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
E, R
- 浓度：
IgG concentration 1.0 mg/ml
- 抗体名：
CD120a antibody | H398
- 规格：
25 µg/0.2 mg
| 规格： | 25 µg | 产品价格： | 询价 |
|---|---|---|---|
| 规格： | 0.2 mg | 产品价格： | 询价 |
Mouse anti Human CD120a antibody, clone H398 recognizes an extracellular domain of the ~55 kDa human TNF receptor (p55, TNF-R1, CD120a). No binding occurs to the ~75 kDa TNF receptor (CD120b). CD120a is weakly expressed by monocytes and granulocytes.
Mouse anti Human CD120a antibody, clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.
Mouse anti Human CD120a antibody, clone H398 inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (Thoma et al. 1990 and Dri et al. 1999).
Mouse anti Human CD120a antibody, clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.
Mouse anti Human CD120a antibody, clone H398 inhibits the biological activity of both natural and recombinant human TNFalpha and TNFbeta (Thoma et al. 1990 and Dri et al. 1999).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | ✓ | ||
| Radioimmunoassays | ✓ |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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文献和实验该产品被引用文献
Source Reference
- Thoma, B. et al. (1990) Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses.
J Exp Med. 172 (4): 1019-23.
References for CD120a antibody
- Menegazzi, R. et al. (1994) Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor.
Blood. 84 (1): 287-93. - Weigert, N. et al. (1996) Gastrin secretion from primary cultures of rabbit antral G cells: stimulation by inflammatory cytokines.
Gastroenterology. 110 (1): 147-54. - Dri, P. et al. (1999) Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst.
J Immunol. 162 (1): 460-6. - Kohrgruber, N. et al. (1999) Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines.
J Immunol. 163 (6): 3250-9. - Schett, G. et al. (2003) TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response.
Cell Death Differ. 10: 1126-36. - Kennedy, G. et al. (2010) Biochemical and vascular aspects of pediatric chronic fatigue syndrome.
Arch Pediatr Adolesc Med. 164 (9): 817-23. - Thiery, J. et al. (2003) Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.
J Immunol. 170: 5919-26. - Gregory, A.P. et al. (2012) TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
Nature. 488 (7412): 508-11.
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Mouse anti Human CD120a，clone H398
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