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- 详细信息
- 技术资料
- 免疫原:
E. coli derived recombinant protein corresponding to amino acids 66-201 of human c-Myc
- 亚型:
IgG1
- 形态:
Purified IgG - liquid
- 克隆性:
PrecisionAb Monoclonal
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
CD01/2A2
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
WB
- 浓度:
IgG concentration 0.5 mg/ml
- 抗体名:
c-Myc antibody | CD01/2A2
- 规格:
100 µl
Mouse anti Human c-Myc antibody recognizes the Myc proto-oncogene protein, also known as avian myelocytomatosis viral oncogene homolog, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, transcription factor p64 or v-myc myelocytomatosis viral oncogene homolog.
The protein encoded by MYC gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma (BL). There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of MYC (provided by RefSeq, Jul 2008).
Mouse anti Human c-Myc antibody detects a band of 57 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The protein encoded by MYC gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma (BL). There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of MYC (provided by RefSeq, Jul 2008).
Mouse anti Human c-Myc antibody detects a band of 57 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
储存信息
This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | ✓ | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Mouse anti c-Myc,clone CD01/2A2
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