Mouse anti Human CCL2,clone AA07-3B8

Mouse anti Human CCL2,clone AA

07-3B8
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  • 询价
  • BIO-RAD已认证
  • MCA6218GA
  • 2025年10月17日
  • E
  • Human
  • 详细信息
  • 技术资料
  • 免疫原

    E. coli derived recombinant human CCL2 (Gln24-Thr99)

  • 亚型

    IgG1

  • 形态

    Purified IgG - liquid

  • 克隆性

    Monoclonal Antibody

  • 标记物

    Purified

  • 适应物种

    Human

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    AA07-3B8

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 应用范围

    E

  • 浓度

    IgG concentration 1.0 mg/ml

  • 抗体名

    CCL2 antibody | AA07-3B8

  • 规格

    0.1 mg

Mouse anti Human CCL2 antibody, clone AA07-3B8, recognizes C-C motif chemokine 2, also known as MCP1, HC11, and MCAF. CCL2 is a constitutively expressed chemokine, which is upregulated during the inflammatory response and promotes recruitment of immune cells to specific sites. Many cell types can produce CCL2, including endothelial, epithelial, myeloid, smooth muscle cells and fibroblasts, and CCL2 is able to recruit monocytes, basophils, T lymphocytes and NK cells (Lim et al. 2016). CCL2 promotes cancer development and metastasis through binding to the cognate receptor CCR2, and CCL2-CCR2 signaling has multiple tumorigenic roles. The tumor microenvironment itself produces CCL2, which facilitates the accumulation of tumor associated macrophages (TAMs), which have immune suppressive and tumor promoting functions (Yoshimura et al. 2018).

The purified Mouse anti Human CCL2 antibody, clone AA07-3B8 (MCA6218GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CCL2 antibody, clone AA03-4H10 (MCA6219B) as the detection antibody.


储存信息

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.


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