Mouse anti Human CD29,clone 4B7R
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Mouse anti Human CD29,clone 4B

7R
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  • 询价
  • BIO-RAD已认证
  • MCA1949T
  • 2025年10月17日
  • F, IF, IP, P *
  • Human
  • 详细信息
  • 文献和实验
  • 技术资料
  • 免疫原

    Occular melanoma cell line V+B2.

  • 亚型

    IgG1

  • 形态

    Purified IgG - liquid

  • 克隆性

    Monoclonal Antibody

  • 标记物

    Purified

  • 适应物种

    Human

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    4B7R

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 应用范围

    F, IF, IP, P *

  • 浓度

    IgG concentration 1.0 mg/ml

  • 抗体名

    CD29 antibody | 4B7R

  • 规格

    25 µg/0.2 mg/0.1 mg

规格:25 µg产品价格:询价
规格:0.2 mg产品价格:询价
规格:0.1 mg产品价格:询价
Mouse anti Human CD29 monoclonal antibody, clone 4B7R recognizes the human integrin beta 1 subunit, also known as CD29, a ~130 kDa (red) 115 kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes and mesenchymal stem cells.

Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathione-S-transferase inhibitor diethyl maleate (Horvath-Arcidiacono et al. 2003)


储存信息

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1/25 1/50
Immunofluorescence
Immunohistology - Paraffin 1
Immunoprecipitation
Western Blotting ×
  1. 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10μl of the suggested working dilution to label 106 cells in 100μl


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图标文献和实验
该产品被引用文献

References for CD29 antibody

  1. Marshall, J.F. et al. (1998) Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas.
    Br J Cancer. 77 (4): 522-9.
  2. Horvath-Arcidiacono, J.A. et al. (2003) Human natural killer cell activity against porcine targets: modulation by control of the oxidation-reduction environment and role of adhesion molecule interactions.
    Cell Immunol. 222: 35-44.
  3. Pillay, J. et al. (2010) Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia.
    J Leukoc Biol. 88: 211-20.
  4. Meng, J. et al. (2011) Contribution of human muscle-derived cells to skeletal muscle regeneration in dystrophic host mice.
    PLoS One. 6(3):e17454.
  5. Kim, B.S. et al. (2011) Effects of the dichloromethane fraction of dipsaci radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells.
    Biosci Biotechnol Biochem. 75:13-9.
  6. Kato, H. et al. (2012) The primacy of β1 integrin activation in the metastatic cascade.
    PLoS One. 7 (10): e46576.
  7. Tan, D.W. et al. (2013) Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells.
    Development. 140 (7): 1433-44.
  8. Yi, T. et al. (2015) Manufacture of Clinical-Grade Human Clonal Mesenchymal Stem Cell Products from Single Colony Forming Unit-Derived Colonies Based on the Subfractionation Culturing Method.
    Tissue Eng Part C Methods. 21 (12): 1251-62.
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Mouse anti Human CD29,clone 4B7R
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