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- 详细信息
- 技术资料
- 免疫原:
E. coli-derived recombinant human cofilin 1 (aa 1-166)
- 亚型:
IgG2a
- 形态:
Purified IgG - liquid
- 克隆性:
PrecisionAb Monoclonal
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
25C1-E3-D3
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
WB
- 浓度:
IgG concentration 0.5 mg/ml
- 抗体名:
Cofilin 1 antibody | 25C1-E3-D3
- 规格:
100 µl
Mouse anti Human cofilin 1 antibody recognizes CFL1, also known as HEL-S-15.
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus (supplied by OMIM, Apr 2004).
Mouse anti Human cofilin 1 antibody detects a band of 18 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus (supplied by OMIM, Apr 2004).
Mouse anti Human cofilin 1 antibody detects a band of 18 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
储存信息
This product is shipped at ambient temperature.
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | ✓ | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Mouse anti Cofilin 1,clone 25C1-E3-D3
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