- 询价
- BIO-RAD
- MCA4705GA
- 2025年10月17日
- C, F, IF, IP
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Mouse intestinal intraepithelial lymphocytes
- 亚型：
IgG
- 形态：
Purified IgG - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Mouse
- 保质期：
自发货之日起 12 个月
- 目录编号：
2E7
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
C, F, IF, IP
- 浓度：
IgG concentration 0.5mg/ml
- 抗体名：
CD103 antibody | 2E7
- 规格：
0.1 mg
Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule αEβ7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The αEβ7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocyes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells. Hamster anti Mouse CD103 antibody, clone 2E7 is expected to also recognize the intact αEβ7 complex.
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | 1/10 | 1/20 |
| Immunofluorescence | ✓ | ||
| Immunohistology - Frozen | ✓ | ||
| Immunoprecipitation | ✓ |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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文献和实验该产品被引用文献
References for CD103 antibody
- Lefrançois, L. et al. (1994) Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells.
Eur J Immunol. 24: 635- 640 - Jung, K. et al. (2011) Peroxisome proliferator-activated receptor γ-mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice.
J Allergy Clin Immunol. 127 (2): 420-429.e1-6. - Moesta, A.K. et al. (2017) Local Delivery of OncoVEX(mGM-CSF) Generates Systemic Antitumor Immune Responses Enhanced by Cytotoxic T-Lymphocyte-Associated Protein Blockade.
Clin Cancer Res. 23 (20): 6190-202.
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文献支持
Hamster anti Mouse CD103，clone 2E7
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