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- 详细信息
- 技术资料
- 免疫原:
A peptide within the N-terminal region of human HMGN2
- 亚型:
HMGN2
- 形态:
Purified IgG - liquid
- 克隆性:
Polyclonal Antibody
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
Polyclonal IgG
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
WB
- 抗体名:
HMGN2 antibody
- 规格:
0.1 ml
Rabbit anti Human HMGN2 antibody recognizes high mobility group nucleosome-binding domain-containing protein 2, also known as non-histone chromosomal protein HMG-17.
HMGN2 is a 9 kDa member of the HMG class of chromosomal proteins, the most abundant non-histones present in the nuclei of eukaryotic cells (Hock et al. 2007). Chromatin regions with high levels of HMGN2 are enriched in transcriptionally active genes and in acetylated histones. HMGN2 associates with actively transcribed genes. HMGN2 also binds to the inner side of the nucleosomal DNA, thereby regulating the interaction between the DNA and the nucleosome. HMGN2 may also play a role in maintaining transcribable genes in a unique chromatin conformation (Garza-Manero et al. 2019).
HMGN2 is a 9 kDa member of the HMG class of chromosomal proteins, the most abundant non-histones present in the nuclei of eukaryotic cells (Hock et al. 2007). Chromatin regions with high levels of HMGN2 are enriched in transcriptionally active genes and in acetylated histones. HMGN2 associates with actively transcribed genes. HMGN2 also binds to the inner side of the nucleosomal DNA, thereby regulating the interaction between the DNA and the nucleosome. HMGN2 may also play a role in maintaining transcribable genes in a unique chromatin conformation (Garza-Manero et al. 2019).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | ✓ | 1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Rabbit anti Human HMGN2
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