Rabbit anti Histone H1.3

Rabbit anti Histone H1.3

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  • 询价
  • BIO-RAD已认证
  • VPA00783
  • 2025年10月17日
  • WB
  • Human
  • 详细信息
  • 技术资料
  • 免疫原

    Synthetic peptide directed towards the N terminal region of human histone H1.3

  • 亚型

    Purified

  • 形态

    Purified IgG - liquid

  • 克隆性

    PrecisionAb Polyclonal

  • 标记物

    Purified

  • 适应物种

    Human

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    Polyclonal IgG

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 应用范围

    WB

  • 浓度

    IgG concentration 0.5 mg/ml.

  • 抗体名

    Histone H1.3 antibody

  • 规格

    100 µl

Rabbit anti Human histone H1.3 antibody recognizes histone H1.3, also known as histone H1c, H1-3 and H1s-2. Histones are the major protein component of chromatin, with important roles in gene regulation. Histone H1 binds to linker DNA between nucleosomes, plays a role in higher-order chromatin stabilization, and is also able to fine-tune gene transcription in a locus-specific way (Brockers and Schneider, 2019). Histone variants replace canonical histones when nucleosomes are disrupted, with diverse implications for epigenetic gene regulation. Histone H1.3 is a histone variant and appears to have diverse roles in cancer. This protein has been suggested as a prognostic biomarker for pancreatic ductal adenocarcinoma (Bauden et al. 2017). Histone H1.3 has also been identified as a repressor for the oncogene H19, contributing to the suppression of epithelial ovarian carcinogenesis (Medrzycki et al. 2015).


储存信息

This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.


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