- 询价
- BIO-RAD
- VPA00889
- 2025年10月17日
- WB
- Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human alpha actinin-1
- 亚型：
Purified
- 形态：
Purified IgG - liquid
- 克隆性：
PrecisionAb Polyclonal
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
Polyclonal IgG
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
WB
- 浓度：
IgG concentration 0.5 mg/ml.
- 抗体名：
Alpha ACTININ-1 antibody
- 规格：
100 µl
Rabbit anti Human alpha actinin-1 antibody recognizes alpha-actinin-1, also known as F-actin cross-linking protein, actinin 1 smooth muscle and alpha-actinin cytoskeletal isoform.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1 (provided by RefSeq, Jul 2008).
Rabbit anti Human alpha actinin-1 antibody detects a band of 100 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1 (provided by RefSeq, Jul 2008).
Rabbit anti Human alpha actinin-1 antibody detects a band of 100 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
储存信息
This product is shipped at ambient temperature.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | ✓ | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Rabbit anti Alpha ACTININ-1
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