Mouse anti Human IgG (Fc) CH2 Domain:FITC,clone MK 1 A6
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Mouse anti Human IgG (Fc) CH2

Domain:FITC,clone MK 1 A6
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  • 询价
  • BIO-RAD已认证
  • MCA647F
  • 2025年10月17日
  • E
  • Human
  • 详细信息
  • 文献和实验
  • 技术资料
  • 免疫原

    Human IgG Polyclonal.

  • 亚型

    IgG1

  • 形态

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

  • 克隆性

    Monoclonal Antibody

  • 标记物

    FITC

  • 适应物种

    Human

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    MK 1 A6

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 应用范围

    E

  • 浓度

    IgG concentration 0.1 mg/ml

  • 抗体名

    IgG antibody | MK 1 A6

  • 规格

    0.1 mg

Mouse anti Human IgG (Fc) CH2 domain, clone MK 1 A6 recognizes human IgG Fc (all subclasses).

CH2 and hinge regions have an important role in effector functions of IgG. The epitope detected by clone MK 1 A6 lies within the CH2 domain as determined by haemagglutination and western blotting using IgG heavy chain and myelomas with defined domain deletions.


储存信息

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/1000 1/10000
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.


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图标文献和实验
该产品被引用文献

References for IgG antibody

  1. Lund, J. et al. (1996) Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma receptor I and influence the synthesis of its oligosaccharide chains.
    J Immunol. 157 (11): 4963-9.
  2. Rasti, N. et al. (2006) Nonimmune immunoglobulin binding and multiple adhesion characterize Plasmodium falciparum-infected erythrocytes of placental origin.
    Proc Natl Acad Sci U S A. 103: 13795-800.
  3. Wozniak-Knopp, G. et al. (2010) Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties.
    Protein Eng Des Sel. 23: 289-97.
  4. Raghuraman, S. et al. (2012) Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion.
    J Infect Dis. 205: 763-71.
  5. Hasenhindl, C. et al. (2013) Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc.
    Protein Eng Des Sel. 26 (10): 675-82.
  6. Traxlmayr, M.W. et al. (2014) Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution.
    Biotechnol J. 9: 1013-22.
  7. Bali, N. et al. (2022) Sticks and Stones, a conserved cell surface ligand for the Type IIa RPTP Lar, regulates neural circuit wiring in Drosophila.
    Elife. 11: e71469.
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Mouse anti Human IgG (Fc) CH2 Domain:FITC,clone MK 1 A6
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